Tag : clinical trials

Pediatrics

St. Jude experimental anti-malarial drug shows promise in first clinical trial

Newsemia
Malaria is a leading killer of children worldwide, and new drugs are needed. New research reports encouraging early clinical results with a new compound. Source...
Biology

Preregistration of exploratory research: Learning from the golden age of discovery

Newsemia
by Ulrich Dirnagl Preregistration of study protocols and, in particular, Registered Reports are novel publishing formats that are currently gaining substantial traction. Besides rating the...
Neurology

FDA OKs First Once-Daily IV COX-2 Preferential NSAID for Pain

Newsemia
The FDA approved meloxicam injection (Anjeso, Baudax Bio) for the treatment of moderate to severe pain, either by itself or with other NSAID analgesics. FDA...
Neurology

Suicidal Patients Often Excluded From Antidepressant Trials

Newsemia
Clinical trials of antidepressants that inform FDA approval decisions often exclude suicidal patients, leaving clinicians uncertain of the efficacy of these drugs in this patient...
Biology

Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative

Newsemia
by Daniel Strech, Tracey Weissgerber, Ulrich Dirnagl, on behalf of QUEST Group The reproducibility crisis triggered worldwide initiatives to improve rigor, reproducibility, and transparency in...
Neurology

Best Treatment for Post-Stroke Depression Still Unclear

Newsemia
Choosing the best treatment option for post-stroke depression is still more art than science, with little evidence to support one approach over another, a new...
Neurology

Maybe Memorizing the Krebs Cycle Was Worthwhile After All

Newsemia
Mitochondrial disorders are often difficult to diagnose and treat due to their multisystem nature. As scientists better understand mitochondrial function, effective treatments are beginning to...
Neurology

Negative Phase 2 Trial Data Ends Development of PSP Drug

Newsemia
Phase 2 trial results show gosuranemab did not meet primary or key secondary endpoints in patients with progressive supranuclear palsy, leading to discontinuation of the...
Neurology

'Spark of Hope' for Tau Inhibitor in Alzheimer's Disease

Newsemia
Low-dose hydromethylthionine may help prevent both cognitive decline and brain atrophy in early Alzheimer’s disease, new exploratory research suggests. Medscape Medical News Source link...
Pediatrics

Stem Cell Therapy Helps Broken Hearts Heal in Unexpected Way

Newsemia
A study in Nature shows stem cell therapy helps hearts recover from a heart attack, although not for the biological reasons originally proposed two decades...
Neurology

The Falls and Frustrations of Progressive Supranuclear Palsy

Newsemia
PSP is a rare neurogenerative disorder that is increasingly appreciated among neurologists. Yet effective treatments remain elusive. Medscape Neurology Source link...
Pediatrics

Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial

Newsemia
The largest-ever clinical trial of a medication for pediatric cardiology patients found that an oral drug significantly improved exercise capacity in adolescent patients with severe,...
Pediatrics

Treating the TOTAL patient: clinical trial reduces relapse

Newsemia
A St. Jude Children’s Research Hospital study lowered the rate of relapse for patients with acute lymphoblastic leukemia. Source link...

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