Tag : clearance

Cardiology

Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.

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Related Articles Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction. Aging Cell. 2019 06;18(3):e12945 Authors: Walaszczyk A,...
Dermatology

Successful and Rapid Clearance of Severe, Treatment-Resistant Atopic Dermatitis with Dupilumab in a 3-Year-Old.

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Related Articles Successful and Rapid Clearance of Severe, Treatment-Resistant Atopic Dermatitis with Dupilumab in a 3-Year-Old. Dermatol Ther. 2020 Sep 05;:e14282 Authors: Dakin H, Haas...
Cardiology

IL-10 provides cardioprotection in diabetic myocardial infarction via upregulation of Heme clearance pathways.

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Related Articles IL-10 provides cardioprotection in diabetic myocardial infarction via upregulation of Heme clearance pathways. JCI Insight. 2020 Sep 03;5(17): Authors: Gupta R, Liu L,...
Biology

Impact of Losing hRpn13 Pru or UCHL5 on Proteasome Clearance of Ubiquitinated Proteins and RA190 Cytotoxicity [Research Article]

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hRpn13/ADRM1 links substrate recruitment with deubiquitination at the proteasome through its proteasome- and ubiquitin-binding Pru domain and DEUBAD domain, which binds and activates deubiquitinating enzyme...
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Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy

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Carare, RO; Aldea, R; Agarwal, N; Bacskai, BJ; Bechman, I; Boche, D; Bu, G; … Verma, A; + view all Carare, RO; Aldea, R; Agarwal,...
Pharma / Biotech

PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: faster PEG shedding attenuates anti-PEG IgM production.

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Related Articles PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: faster PEG shedding attenuates anti-PEG IgM production. Int J Pharm. 2020 Aug 19;:119792...
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Studies of experimental cerebral ischaemia using nuclear magnetic resonance and hydrogen clearance.

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Allen, Kathryn Louise; (1992) Studies of experimental cerebral ischaemia using nuclear magnetic resonance and hydrogen clearance. Doctoral thesis (Ph.D.), Institute of Neurology. Green open access...
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Graphene oxide enhances β-amyloid clearance by inducing autophagy of microglia and neurons

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Li, X; Li, K; Chu, F; Huang, J; Yang, Z; (2020) Graphene oxide enhances β-amyloid clearance by inducing autophagy of microglia and neurons. Chemico-Biological Interactions...
Pharma / Biotech

The bioavailability and maturing clearance of doxapram in preterm infants.

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Related Articles The bioavailability and maturing clearance of doxapram in preterm infants. Pediatr Res. 2020 Jul 22;: Authors: Flint RB, Simons SHP, Andriessen P, Liem...
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Inotrem Receives Clearance From French, Belgian And US Authorities to Launch a Phase II Clinical Trial Aimed at Assessing Nangibotide in Mechanically Ventilated Patients With COVID-19

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PARIS–(BUSINESS WIRE)– #PIA–Inotrem launches a Phase II clinical trial to assess nangibotide in Covid-19 patients. Trial will take place in France, Belgium, and the USA....

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