Tag : chromatographytandem

Pharma / Biotech

Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for characterizing caffeine, methylliberine, and theacrine pharmacokinetics in humans.

Newsemia
Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for characterizing caffeine, methylliberine, and theacrine pharmacokinetics in humans. J Chromatogr B Analyt Technol Biomed Life...
Pharma / Biotech

Bioanalytical method development and validation of a liquid chromatography-tandem mass spectrometry method for determination of β-lapachone in human plasma.

Newsemia
Related Articles Bioanalytical method development and validation of a liquid chromatography-tandem mass spectrometry method for determination of β-lapachone in human plasma. J Pharm Biomed Anal....
Pharma / Biotech

Determination of the immunostimulatory drug – Glucosoaminyl-Muramyl-Dipeptide – in human plasma using high performance liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.

Newsemia
Related Articles Determination of the immunostimulatory drug – Glucosoaminyl-Muramyl-Dipeptide – in human plasma using high performance liquid chromatography-tandem mass spectrometry and its application to a...
Pharma / Biotech

Validation of a universal and highly sensitive two-dimensional liquid chromatography-tandem mass spectrometry methodology for the quantification of pyrazinamide, ethambutol, protionamide, and clofazimine in different biological matrices.

Newsemia
Related Articles Validation of a universal and highly sensitive two-dimensional liquid chromatography-tandem mass spectrometry methodology for the quantification of pyrazinamide, ethambutol, protionamide, and clofazimine in...
Pharma / Biotech

Bioanalytical assay for the new-generation ROS1/TRK/ALK inhibitor repotrectinib in mouse plasma and tissue homogenate using liquid chromatography-tandem mass spectrometry.

Newsemia
Related Articles Bioanalytical assay for the new-generation ROS1/TRK/ALK inhibitor repotrectinib in mouse plasma and tissue homogenate using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt...
Pharma / Biotech

Determination of Oroxylin A, Oroxylin A 7-O-glucuronide, and Oroxylin A sodium sulfonate in beagle dogs via ultra-high-performance liquid chromatography/tandem mass spectrometry: Application in a pharmacokinetic study.

Newsemia
Related Articles Determination of Oroxylin A, Oroxylin A 7-O-glucuronide, and Oroxylin A sodium sulfonate in beagle dogs via ultra-high-performance liquid chromatography/tandem mass spectrometry: Application in...
Pharma / Biotech

Liquid chromatography-tandem mass spectrometry bioanalytical method for the determination of kavain in mice plasma: Application to a pharmacokinetic study.

Newsemia
Related Articles Liquid chromatography-tandem mass spectrometry bioanalytical method for the determination of kavain in mice plasma: Application to a pharmacokinetic study. J Chromatogr B Analyt...
Pharma / Biotech

Liquid chromatography-tandem mass spectrometric method for the quantification of eliglustat in rat plasma and the application in a pre-clinical study.

Newsemia
Related Articles Liquid chromatography-tandem mass spectrometric method for the quantification of eliglustat in rat plasma and the application in a pre-clinical study. J Pharm Biomed...
Pharma / Biotech

Determination of mycophenolic acid in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and its pharmacokinetic application in kidney transplant patients.

Newsemia
Related Articles Determination of mycophenolic acid in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and its pharmacokinetic application in kidney transplant patients. Biomed...
Pharma / Biotech

Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry.

Newsemia
Related Articles Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2019 Jul 16;176:112735...
Pharma / Biotech

Pharmacokinetic study of six triterpenoids of raw and processed Alisma plantago-aquatica in rat plasma by using ultra performance liquid chromatography-tandem mass spectrometry approach.

Newsemia
Related Articles Pharmacokinetic study of six triterpenoids of raw and processed Alisma plantago-aquatica in rat plasma by using ultra performance liquid chromatography-tandem mass spectrometry approach....
Pharma / Biotech

Liquid chromatography-tandem mass spectrometry to assess the pharmacokinetics and tissue distribution of withaferin A in rats.

Newsemia
Related Articles Liquid chromatography-tandem mass spectrometry to assess the pharmacokinetics and tissue distribution of withaferin A in rats. J Chromatogr B Analyt Technol Biomed Life...
Pharma / Biotech

Bioanalytical assay for the novel TRK inhibitor selitrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

Newsemia
Related Articles Bioanalytical assay for the novel TRK inhibitor selitrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt...
Cardiology

Precursor ion scan enhanced rapid identification of the chemical constituents of Danhong injection by liquid chromatography-tandem mass spectrometry: An integrated strategy.

Newsemia
Related Articles Precursor ion scan enhanced rapid identification of the chemical constituents of Danhong injection by liquid chromatography-tandem mass spectrometry: An integrated strategy. J Chromatogr...
Pharma / Biotech

Simultaneous quantification of tegoprazan and its major metabolite M1 in dog plasma using liquid chromatography-tandem mass spectrometry.

Newsemia
Simultaneous quantification of tegoprazan and its major metabolite M1 in dog plasma using liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2019 Mar 21;171:99-103 Authors:...
Pharma / Biotech

Quantitative determination and pharmacokinetic study of fusaricidin A in mice plasma and tissues using ultra-high performance liquid chromatography-tandem mass spectrometry.

Newsemia
Related Articles Quantitative determination and pharmacokinetic study of fusaricidin A in mice plasma and tissues using ultra-high performance liquid chromatography-tandem mass spectrometry. J Pharm Biomed...
Pharma / Biotech

A high-performance liquid chromatography-tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine and its application in clinical pharmacokinetic study.

Newsemia
Related Articles A high-performance liquid chromatography-tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and...
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Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the quantitative analysis of mammalian-derived inositol poly/pyrophosphates

Newsemia
Ito, M; Fujii, N; Wittwer, C; Sasaki, A; Tanaka, M; Bittner, T; Jessen, HJ; … Nagata, E; + view all Ito, M; Fujii, N; Wittwer,...
Pharma / Biotech

A rapid and sensitive liquid chromatography/tandem mass spectrometry assay for simultaneous quantitation of disopyramide and its major metabolite, mono-isopropyl-disopyramide, in rat plasma and its application to a pharmacokinetic study.

Newsemia
Related Articles A rapid and sensitive liquid chromatography/tandem mass spectrometry assay for simultaneous quantitation of disopyramide and its major metabolite, mono-isopropyl-disopyramide, in rat plasma and...

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