Tag : Chromatin

Biology

Mutual Balance of Histone Deacetylases 1 and 2 and the Acetyl Reader ATAD2 Regulates the Level of Acetylation of Histone H4 on Nascent Chromatin of Human Cells [Research Article]

Newsemia
Newly synthesized histone H4 that is incorporated into chromatin during DNA replication is acetylated on lysines 5 and 12. Histone deacetylase 1 (HDAC1) and HDAC2...
Gastroenterology

BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling

Newsemia
BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling Source link...
AI/ML

Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data.

Newsemia
Related Articles Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data. Nat Commun. 2020 Mar 03;11(1):1173 Authors: Ashoor H, Chen X,...
Biology

Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize

Newsemia
by Yalin Liu, Handong Su, Jing Zhang, Yang Liu, Chao Feng, Fangpu Han In most plants, centromeric DNA contains highly repetitive sequences, including tandem repeats...
Dentistry

MLH1-mediated recruitment of FAN1 to chromatin for the induction of apoptosis triggered by O6 -methylguanine.

Newsemia
Related Articles MLH1-mediated recruitment of FAN1 to chromatin for the induction of apoptosis triggered by O6 -methylguanine. Genes Cells. 2020 Jan 19;: Authors: Rikitake M,...
Biology

Experimental evolution reveals a general role for the methyltransferase Hmt1 in noise buffering

Newsemia
by Shu-Ting You, Yu-Ting Jhou, Cheng-Fu Kao, Jun-Yi Leu Cell-to-cell heterogeneity within an isogenic population has been observed in prokaryotic and eukaryotic cells. Such heterogeneity...
Biology

Calcineurin Broadly Regulates the Initiation of Skeletal Muscle-Specific Gene Expression by Binding Target Promoters and Facilitating the Interaction of the SWI/SNF Chromatin Remodeling Enzyme [Research Article]

Newsemia
Calcineurin (Cn) is a calcium-activated serine/threonine protein phosphatase that is broadly implicated in diverse cellular processes, including the regulation of gene expression. During skeletal muscle...

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