Tag: Chimeric

Gastroenterology

Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice

Newsemia
Glypican 3 (GPC3) is an oncofetal antigen involved in Wnt-dependent cell proliferation that is highly expressed in hepatocellular carcinoma (HCC). We investigated whether the functions...
Biology

Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody

Newsemia
by Sunita Gulati, Frank J. Beurskens, Bart-Jan de Kreuk, Marcel Roza, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Nancy A. Nowak, Ronald P. Taylor, Marina...
Biology

Emergence of a Chimeric Globin Pseudogene and Increased Hemoglobin Oxygen Affinity Underlie the Evolution of Aquatic Specializations in Sirenia

Newsemia
Abstract As limits on O2 availability during submergence impose severe constraints on aerobic respiration, the oxygen binding globin proteins of marine mammals are expected to...
Biology

Mutations, Differential Gene Expression, and Chimeric Transcripts in Esophageal Squamous Cell Carcinoma Show High Heterogeneity.

Newsemia
Related Articles Mutations, Differential Gene Expression, and Chimeric Transcripts in Esophageal Squamous Cell Carcinoma Show High Heterogeneity. Transl Oncol. 2018 Aug 29;11(6):1283-1291 Authors: Souza-Santos PT,...

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