Tag : characterization

Pharma / Biotech

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: a Pharmacokinetic, Microbiome and Untargeted Metabolomics Study.

Newsemia
Related Articles Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: a Pharmacokinetic, Microbiome and Untargeted Metabolomics Study. Clin Transl Sci. 2020...
Biology

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

Newsemia
by Linxiang Yin, Geoffrey Masuyer, Sicai Zhang, Jie Zhang, Shin-Ichiro Miyashita, David Burgin, Laura Lovelock, Shu-Fen Coker, Tian-min Fu, Pål Stenmark, Min Dong Botulinum neurotoxins...
Neurology

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Newsemia
Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic...
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Pore structure characterization and transport performance simulation of cement hydration based on irregular particles

Newsemia
Liu, Z; Chen, W; Lv, H; Zhang, Y; Liu, C; (2018) Pore structure characterization and transport performance simulation of cement hydration based on irregular particles....
Gastroenterology

P159 PHENOTYPIC CHARACTERIZATION OF INFLAMMATORY BOWEL DISEASE BIOPSIES REVEAL THAT MAST CELLS ARE SIGNIFICANTLY ELEVATED AND ACTIVATED IN PATIENTS WITH ULCERATIVE COLITIS

Newsemia
Accumulation and activation of mast cells and eosinophils have been implicated in the pathogenesis of several chronic inflammatory gastrointestinal (GI) diseases, including eosinophilic gastrointestinal diseases...
Gastroenterology

P065 CHARACTERIZATION OF EARLY CLINICAL AND PHARMACOKINETIC RESPONSE PROFILES OF VEDOLIZUMAB: AN INTERIM ANALYSIS OF ENTERPRET, A PHASE 4 CLINICAL STUDY

Newsemia
Vedolizumab (VDZ), a gut-selective antibody that binds specifically to integrin α4β7, is approved for treatment of adults with moderate-to-severe ulcerative colitis (UC). An association between...
Biology

Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment [SHORT COMMUNICATION]

Newsemia
Petra M. Hermann, Alexander C. Perry, Izen Hamad, and Willem C. Wildering Plasma membrane efflux transporters play crucial roles in the removal and release of...
Biology

Rainbow trout slow myoblast cell culture as a model to study slow skeletal muscle, and the characterization of mir-133 and mir-499 families as a case study [RESEARCH ARTICLE]

Newsemia
Bruno Oliveira da Silva Duran, Maeli Dal-Pai-Silva, and Daniel Garcia de la serrana Muscle fibres are classified as fast, intermediate and slow. In vitro myoblast...
Biology

Genedata Expressionist Enhances Automated Characterization of Biopharmaceuticals by Mass Spectrometry

Newsemia
WASHINGTON (PRWEB) January 28, 2020 Genedata, the leading provider of enterprise software solutions for biopharmaceutical R&D, today announced the release of Genedata Expressionist ® 13.5...
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Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness

Newsemia
Al Maskari, R; Hardege, I; Cleary, S; Figg, N; Li, Y; Siew, K; Khir, A; … Yasmin, ; + view all Al Maskari, R; Hardege,...

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