Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases
by Robin A. Welsh, Nianbin Song, Catherine A. Foss, Tatiana Boronina, Robert N. Cole, Scheherazade Sadegh-Nasseri DO (HLA-DO, in human; murine H2-O) is a highly...
Tag : central nervous system
New therapeutic strategy for lung cancer and associated secondary tumors
In 20 – 40% of patients with cancer, metastasis (the development of secondary tumors) in the central nervous system (CNS) occurs. CNS metastatis impacts negatively...
A new function identified for glycine receptors during embryonic development
Glycine receptors are one of the most widely distributed inhibitory receptors in the central nervous system and have important roles in a variety of physiological...
New standards needed for improving the design of clinical trials for MS patients
How can the perspectives of patients with multiple sclerosis (MS) be given more consideration in clinical trials? This question was investigated and corresponding recommendations were...
Methamphetamine undermines success in treatment for opioid-use disorder
Judith Tsui, a UW Medicine clinician specializing in addiction treatment, was seeing more and more patients she was treating for opioid-use disorder also using methamphetamines,...
Comparative study finds three anti-seizure drugs to be equally safe and effective
A new study finds that the three most common treatment options administered in the emergency department for patients who experience refractory status epilepticus are equally...
New method for correcting hypoxic conditions of the central nervous system
Hypoxia is a key factor that accompanies most brain pathologies, including ischemia and neurodegenerative diseases. Source link...
New technique to detect common cause for diseases related to thrombotic microangiopathies
There is a group of diseases whose symptoms have a common origin: a lesion in the endothelial tissue that covers the inside of the blood...
Syphilis rates in patients with kidney failure found to be greater than general population
Syphilis rates, like other sexually transmitted disease rates in the United States, are soaring, and the first known study to examine syphilis rates in patients...
NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity
by Marjan Gharagozloo, Shaimaa Mahmoud, Camille Simard, Kenzo Yamamoto, Diwakar Bobbala, Subburaj Ilangumaran, Matthew D. Smith, Albert Lamontagne, Samir Jarjoura, Jean-Bernard Denault, VĆ©ronique Blais, Louis...
Surgery crucial for people with drug-resistant epilepsy
Epilepsy is a chronic, central nervous system or neurological disorder wherein the brain activity becomes impaired, leading to seizures. In some cases, it leads to...
New mechanisms to enable regeneration of injured nerve fibers
Injuries to nerve fibers in the brain, spinal cord, and optic nerves usually result in functional losses as the nerve fibers are unable to regenerate....
Gut microbiota protects from viral-induced neurologic damage, study finds
Gut microbes produce compounds that prime immune cells to destroy harmful viruses in the brain and nervous system, according to a mouse study published today...
Schwann cells capable of generating protective myelin over nerves finds research
Researchers have found that Schwann cells, a special type of cells are capable of generating protective myelin sheath covers for the nerves at rates higher...
Scientists discover how Schwann cells generate myelin at the molecular level
Scientists have discovered that a special type of cell is much more prolific in generating a protective sheath covering nerve fibers than previously believed. Source...
The interleukin-4/PPARĪ³ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury
by Qingxiu Zhang, Wen Zhu, Fei Xu, Xuejiao Dai, Ligen Shi, Wei Cai, Hongfeng Mu, T. Kevin Hitchens, Lesley M. Foley, Xiangrong Liu, Fang Yu,...