Tag : Cells

Gastroenterology

Prostaglandin E2, Produced by Mast Cells in Colon Tissues from Patients with Irritable Bowel Syndrome, Contributes to Visceral Hypersensitivity in Mice

Newsemia
Visceral hypersensitivity is common in patients with irritable bowel syndrome (IBS). We investigated whether inflammatory molecules, such as histamine and proteases, activate prostaglandin-endoperoxide synthase 2...
Gastroenterology

7 LACTOBACILLUS REUTERI SUPPRESSES PRO-INFLAMMATORY DRIVEN REACTIVE OXYGEN SPECIES IN VITRO IN HUMAN INTESTINAL EPITHELIAL CELLS AND IN VIVO IN A TNBS COLITIS MOUSE MODEL

Newsemia
Reactive oxygen species (ROS) play a role in maintaining intestinal epithelial homeostasis and are normally kept at low levels via antioxidant compounds. Dysregulation of ROS...
Gastroenterology

12 A FUNCTIONAL TL1A/DR3 SYSTEM IS CRUCIAL FOR OPTIMAL GENERATION OF PATHOGENIC TH9 CELLS IN MURINE CROHN'S DISEASE-LIKE ILEITIS

Newsemia
Despite numerous therapeutic advancements, inflammatory bowel disease (IBD) remains a major health burden due to the inefficiency of conventional therapies. We recently demonstrated the role...
Latest News

Scientists create world’s first model of pituitary disease using human iPS cells

Newsemia
Researchers at Kobe University’s Graduate School of Medicine have developed the world’s first congenital pituitary hypoplasia model using patient-derived iPS cells. Source link...
Gastroenterology

Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice

Newsemia
Glypican 3 (GPC3) is an oncofetal antigen involved in Wnt-dependent cell proliferation that is highly expressed in hepatocellular carcinoma (HCC). We investigated whether the functions...
Latest News

Free radicals from immune cells linked to salt-sensitive hypertension

Newsemia
In salt-sensitive hypertension, immune cells gather in the kidneys and shoot out free radicals, heightening blood pressure and damaging this pair of vital organs, scientists...
Biology

Dynamic changes in cytoskeleton proteins of olfactory ensheathing cells induced by radiofrequency electromagnetic fields [RESEARCH ARTICLE]

Newsemia
Rosaria Grasso, Rosalia Pellitteri, Santi A. Caravella, Francesco Musumeci, Giuseppina Raciti, Agata Scordino, Giovanni Sposito, Antonio Triglia, and Agata Campisi Several evidences have suggested the...
Gastroenterology

P160 γδ T CELLS, IL-22, THE PROBIOTIC, LACTOBACILLUS DELBRUECKII, AND THE ROLE THEY PLAY IN ATTENUATION OF ALCOHOL INDUCED EXACERBATION OF DSS-COLITIS

Newsemia
Ulcerative colitis is characterized by cycles of active disease flare and inactive disease remission. During UC remission, IL-22 expression can be upregulated, acting as a...

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