Tag : Cell Line

AI/ML

MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40.

Newsemia
Related Articles MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40. Cell Transplant. 2019 Dec;28(1_suppl):37S-50S Authors: Zhang...
Cardiology

Hexokinase II Upregulation Contributes to Asiaticoside-Induced Protection of H9c2 Cardioblasts During Oxygen-Glucose Deprivation/Reoxygenation.

Newsemia
Related Articles Hexokinase II Upregulation Contributes to Asiaticoside-Induced Protection of H9c2 Cardioblasts During Oxygen-Glucose Deprivation/Reoxygenation. J Cardiovasc Pharmacol. 2020 01;75(1):84-90 Authors: Zhang J, Yao M,...
Pharma / Biotech

AS1411 Aptamer/Hyaluronic Acid-Bifunctionalized Microemulsion Co-Loading Shikonin and Docetaxel for Enhanced Antiglioma Therapy.

Newsemia
Related Articles AS1411 Aptamer/Hyaluronic Acid-Bifunctionalized Microemulsion Co-Loading Shikonin and Docetaxel for Enhanced Antiglioma Therapy. J Pharm Sci. 2019 11;108(11):3684-3694 Authors: Wang H, Zhu Z, Zhang...
Cardiology

MicroRNA-221 promotes myocardial apoptosis caused by myocardial ischemia-reperfusion by down-regulating PTEN.

Newsemia
Related Articles MicroRNA-221 promotes myocardial apoptosis caused by myocardial ischemia-reperfusion by down-regulating PTEN. Eur Rev Med Pharmacol Sci. 2019 May;23(9):3967-3975 Authors: Kong QR, Ji DM,...
AI/ML

Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes.

Newsemia
Related Articles Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes. Free Radic Biol Med. 2019 11 20;144:245-255 Authors: Martinez Fernandez A, Regazzoni L, Brioschi...
AI/ML

Co-expression of key gene modules and pathways of human breast cancer cell lines.

Newsemia
Related Articles Co-expression of key gene modules and pathways of human breast cancer cell lines. Biosci Rep. 2019 07 31;39(7): Authors: Wu Y, Liu F,...
Pharma / Biotech

Molecular Engineering of an Organic NIR-II Fluorophore with Aggregation-Induced Emission Characteristics for In Vivo Imaging.

Newsemia
Related Articles Molecular Engineering of an Organic NIR-II Fluorophore with Aggregation-Induced Emission Characteristics for In Vivo Imaging. Small. 2019 05;15(20):e1805549 Authors: Wu W, Yang Y,...
Pharma / Biotech

Doxorubicin-loading core-shell pectin nanocell: A novel nanovehicle for anticancer agent delivery with multidrug resistance reversal.

Newsemia
Related Articles Doxorubicin-loading core-shell pectin nanocell: A novel nanovehicle for anticancer agent delivery with multidrug resistance reversal. PLoS One. 2020;15(6):e0235090 Authors: Ouyang J, Yang M,...
Cardiology

Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart

Newsemia
Related Articles Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart JCI Insight. 2019 08 08;4(15):e128722 Authors: Khalil H, Kanisicak O, Vagnozzi...
Cardiology

microRNA-340-5p inhibits hypoxia/reoxygenation-induced apoptosis and oxidative stress in cardiomyocytes by regulating the Act1/NF-κB pathway.

Newsemia
Related Articles microRNA-340-5p inhibits hypoxia/reoxygenation-induced apoptosis and oxidative stress in cardiomyocytes by regulating the Act1/NF-κB pathway. J Cell Biochem. 2019 09;120(9):14618-14627 Authors: Li D, Zhou...
Pharma / Biotech

Hyaluronic acid modified doxorubicin loaded Fe3O4 nanoparticles effectively inhibit breast cancer metastasis.

Newsemia
Related Articles Hyaluronic acid modified doxorubicin loaded Fe3O4 nanoparticles effectively inhibit breast cancer metastasis. J Mater Chem B. 2019 10 14;7(38):5861-5872 Authors: Gong T, Dong...
Pharma / Biotech

Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles.

Newsemia
Related Articles Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles. J Pharm Sci. 2019 09;108(9):3091-3098 Authors: Nittayacharn P, Yuan HX, Hernandez C, Bielecki P, Zhou H,...
Dentistry

A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition.

Newsemia
Related Articles A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition. Cancer Res. 2020 02 15;80(4):757-770 Authors: Kitchen P, Lee KY,...
Pharma / Biotech

Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of Prothionamide.

Newsemia
Related Articles Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of Prothionamide. J Pharm Sci. 2019 09;108(9):3106-3111 Authors: Hasanuzzaman...
Dentistry

Formononetin induces apoptotic cell death through the suppression of mitogen‑activated protein kinase and nuclear factor‑κB phosphorylation in FaDu human head and neck squamous cell carcinoma cells.

Newsemia
Related Articles Formononetin induces apoptotic cell death through the suppression of mitogen‑activated protein kinase and nuclear factor‑κB phosphorylation in FaDu human head and neck squamous...
Cardiology

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes.

Newsemia
Related Articles Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes. Cell Death Dis. 2019 11 04;10(11):835 Authors: Park...
Pharma / Biotech

New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments.

Newsemia
Related Articles New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments. Theranostics. 2019;9(18):5332-5346 Authors:...
AI/ML

Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images.

Newsemia
Related Articles Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images. Sci Rep. 2019 02 07;9(1):1570 Authors:...
AI/ML

The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents.

Newsemia
Related Articles The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents. Clin Cancer Res. 2019 08 15;25(16):5167-5176 Authors: Spriano F, Chung EYL, Gaudio E,...
AI/ML

Substrate stiffness directs diverging vascular fates.

Newsemia
Related Articles Substrate stiffness directs diverging vascular fates. Acta Biomater. 2019 09 15;96:321-329 Authors: Wong L, Kumar A, Gabela-Zuniga B, Chua J, Singh G, Happe...

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