Tag: CD19

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Generon Presented Pre-Clinical Immunotherapy Results With CD3-Activating Bi-Specific Antibody Targeting CD19 on B Cells in Mono- and Bi-Valent Format

SHANGHAI–(BUSINESS WIRE)–#AmericanSocietyOfHematology–Generon presented pre-clinical immunotherapy results with CD3-activating bi-specific antibody targeting CD19 on B cells Source link...

CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum [Research Article]

We previously described a mechanism of acquired resistance of B-cell acute lymphoblastic leukemia to CD19-directed chimeric antigen receptor T-cell (CART) immunotherapy. It was based on...

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