Tag : Carcinomas

Gastroenterology

LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas

Newsemia
LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas Source link...
Gastroenterology

Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice

Newsemia
Glypican 3 (GPC3) is an oncofetal antigen involved in Wnt-dependent cell proliferation that is highly expressed in hepatocellular carcinoma (HCC). We investigated whether the functions...
Biology

Targeting oxidative pentose phosphate pathway prevents recurrence in mutant <i>Kras</i> colorectal carcinomas

Newsemia
by WenChao Gao, YuTing Xu, Tao Chen, ZunGuo Du, XiuJuan Liu, ZhiQian Hu, Dong Wei, ChunFang Gao, Wei Zhang, QingQuan Li Recurrent tumors originate from...
Gastroenterology

Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice

Newsemia
Little is known about the composition and generation of plasma cell subsets in patients with hepatocellular carcinoma (HCC) and how these associate with outcome. We...
Biology

EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers

Newsemia
by Min Pan, Henrik Schinke, Elke Luxenburger, Gisela Kranz, Julius Shakhtour, Darko Libl, Yuanchi Huang, Aljaž Gaber, Miha Pavšič, Brigita Lenarčič, Julia Kitz, Mark Jakob,...

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