Tag : Carcinogenesis

Gastroenterology

Autophagy of Intestinal Epithelial Cells Inhibits Colorectal Carcinogenesis Induced by Colibactin-producing Escherichia coli in ApcMin/+ Mice

Newsemia
Infection with colibactin-producing Escherichia coli promotes autophagy of intestinal epithelial cells, which is required to prevent the carcinogenic effects of these bacteria. Source link...
Biology

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

Newsemia
by Yu Chen, Maud Vandereyken, Ian P. Newton, Ignacio Moraga, Inke S. Näthke, Mahima Swamy Interleukin-22 (IL-22) is a critical immune defence cytokine that maintains...
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IDIBELL researchers identify involvement of cell membrane protein in liver cancer

Newsemia
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have just described for the first time the crucial involvement of a cell membrane protein in the...
Gastroenterology

Mutated CEACAMs Disrupt Transforming Growth Factor beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis

Newsemia
We studied interactions among proteins of the carcinoembryonic antigen related cell adhesion molecule (CEACAM) family, which interact with microbes, and transforming growth factor beta (TGFB)...
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Genetically tweaking gut bacteria reduces risk of colorectal cancer in mice finds study

Newsemia
Researchers have found that editing of the genes of the bacteria present in the guts of mice could help reduce the inflammation and associated risk...

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