Tag : Bowel

Gastroenterology

P066 GB004, A NOVEL GUT-TARGETED PROLYL HYDROXYLASE INHIBITOR FOR INFLAMMATORY BOWEL DISEASE: FIRST-IN-HUMAN, MUTLIPLE-DOSE STUDY IN HEALTHY SUBJECTS WITH GUT BIOPSIES

Newsemia
GB004 is a small molecule prolyl hydroxylase inhibitor (PHDi) that stabilizes hypoxia inducible factors (HIF1-α), key transcription factors involved in the protective cellular responses at...
Gastroenterology

P062 A SYSTEMATIC REVIEW ON POWER ESTIMATION TO SUPPORT SAMPLE SIZE CALCULATION FOR RANDOMISED TRIALS IN INFLAMMATORY BOWEL DISEASE

Newsemia
Inflammatory bowel disease is a collection of disorders of the gastrointestinal tract, characterised by relapsing and remitting inflammation. Studies have reported several pharmacological or non-pharmacological...
Gastroenterology

Group cognitive behavioural therapy (GCBT) versus treatment as usual (TAU) in the treatment of irritable bowel syndrome (IBS): a study protocol for a randomized controlled trial

Newsemia
Irritable bowel syndrome (IBS) is a common disease that affects the quality of life (QOL) and social functioning of sufferers. Visceral anxiety is currently considered...
Gastroenterology

27 UTILIZATION OF AN ELECTONIC MEDICAL RECORD (EMR)-INTEGRATED DASHBOARD IMPROVES IDENTIFICATION AND TREATMENT OF IRON DEFICIENCY IN PEDIATRIC INFLAMMATORY BOWEL DISEASE

Newsemia
Anemia is frequently encountered in inflammatory bowel disease (IBD) with studies reporting an even greater prevalence among children (16-72%) than adults (4-67%) at any given...
Gastroenterology

P016 IMPROVING TUBERCULOSIS RE SCREENING IN INFLAMMATORY BOWEL DISEASE PATIENTS RECEIVING BIOLOGIC THERAPY: A SINGLE CENTER QUALITY IMPROVEMENT INITIATIVE.

Newsemia
Biological agents have revolutionized the management of inflammatory bowel disease (IBD). There is a known increased risk of tuberculosis (TB) reactivation with biologic therapy (1)....
Gastroenterology

P009 FINANCIAL VOLATILITY OF INFLAMMATORY BOWEL DISEASES VS OTHER CHRONIC GASTROINTESTINAL DISEASES – USING THE BETA COEFFICIENT TO CATEGORIZE GI DISORDERS

Newsemia
Symptomatic chronic diseases differ in their propensity for serious costly morbidity. Reliable and predictable deterioration presentations can be associated with very narrow margins between symptoms...
Gastroenterology

P121 REAL WORLD PREVALENCE OF BOWEL MOVEMENT URGENCY – A SNAPSHOT OF SYMPTOM EXPERIENCE REPORTED BY PATIENTS WITH ULCERATIVE COLITIS PARTICIPATING IN SPARC IBD

Newsemia
Urgency, also referred to as bowel movement urgency or bowel urgency, is the sudden need for a bowel movement. Bowel urgency is one of the...

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