Tag: bevacizumab

Gastroenterology

Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer

Newsemia
Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer Source link...
Pharma / Biotech

Correlation Between Bevacizumab Exposure and Survival in Patients with Metastatic Colorectal Cancer.

Newsemia
Correlation Between Bevacizumab Exposure and Survival in Patients with Metastatic Colorectal Cancer. Oncologist. 2020 Apr 09;: Authors: Papachristos A, Kemos P, Kalofonos H, Sivolapenko G...
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Advanced Ovarian Cancer: Survival & NAC Use Continue to Increase

Newsemia
Survival of patients with advanced ovarian cancer continues to increase, despite concerns that increased use of neoadjuvant chemotherapy (NAC) could have a negative impact on...
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Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

Newsemia
To establish a molecular signature of this resistance in ovarian cancer, the authors developed preclinical tumor models of adaptive resistance to chronic anti-VEGF treatment. Source...
Gastroenterology

Combination therapy improves survival in patients with hepatocellular carcinoma

Newsemia
Combination therapy with the PD-L1 inhibitor atezolizumab and the VEGF inhibitor bevacizumab significantly improves overall survival and progression-free survival in patients with unresectable hepatocellular carcinoma...
Gastroenterology

Intravenous Bevacizumab Reduces Transfusion Requirements and Endoscopic Interventions in Patients With Gastric Antral Vascular Ectasia and Small Bowel Angioectasia

Newsemia
Intravenous Bevacizumab Reduces Transfusion Requirements and Endoscopic Interventions in Patients With Gastric Antral Vascular Ectasia and Small Bowel Angioectasia Source link...
AI/ML

Imaging biomarkers of adiposity and sarcopenia as potential predictors for overall survival among patients with endometrial cancer treated with bevacizumab.

Newsemia
Related Articles Imaging biomarkers of adiposity and sarcopenia as potential predictors for overall survival among patients with endometrial cancer treated with bevacizumab. Gynecol Oncol Rep....
Neurology

Fremanezumab May Reduce Attacks in Tough-to-Treat Migraine

Newsemia
The CGRP-targeting migraine-prevention drug fremanezumab is safe and effective in reducing migraines for patients who have failed up to four other therapies, new research shows....
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LYNPARZA® (olaparib) Phase 3 PAOLA-1 Trial Significantly Increased Progression-Free Survival as First-Line Maintenance Treatment with Bevacizumab for Newly-Diagnosed Advanced Ovarian Cancer

Newsemia
KENILWORTH, N.J.–(BUSINESS WIRE)—- $MRK #MRK–LYNPARZA PAOLA-1 Trial Significantly Increased PFS as 1st-Line Maintenance Treatment with Bevacizumab for Newly-Diagnosed Advanced Ovarian Cancer Source link...
Pharma / Biotech

Enhanced anti-angiogenic effects of bevacizumab in glioblastoma treatment upon intranasal administration in polymeric nanoparticles.

Newsemia
Related Articles Enhanced anti-angiogenic effects of bevacizumab in glioblastoma treatment upon intranasal administration in polymeric nanoparticles. J Control Release. 2019 Jul 22;: Authors: Sousa F,...
Gastroenterology

Capecitabine plus bevacizumab versus capecitabine in maintenance treatment for untreated characterised KRAS exon 2 wild-type metastatic colorectal cancer: a retrospective analysis in Chinese postmenopausal women

Newsemia
Capecitabine plus bevacizumab (CAP-B) maintenance treatment after 6 cycles of capecitabine, oxaliplatin, and bevacizumab (CAPOXB) has demonstrated clinical activity and failure to compromise quality of life...
Neurology

Off-Label Drug Research Generates 'Medical Uncertainty'

Newsemia
Research that explores/supports off-label use of pregabalin and other medications may be misleading if early promising results are not subsequently validated, investigators suggest in a...
Cardiology

Role of renin-angiotensin system antagonists in the prevention of bevacizumab and sunitinib mediated cardiac dysfunction.

Newsemia
Role of renin-angiotensin system antagonists in the prevention of bevacizumab and sunitinib mediated cardiac dysfunction. Am J Physiol Heart Circ Physiol. 2018 Nov 30;: Authors:...

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