Remdesivir Might Be a Good Bet Against COVID-19
New research sheds light on why the experimental drug remdesivir might become the most powerful weapon in the fight against COVID-19 Source link...
Tag: bet
STAT Plus: Blackstone Group invests up to $2 billion in Alnylam, a big bet on the Cambridge biotech
The private equity firm Blackstone Group is investing up to $2 billion in Alnylam Pharmaceuticals, a big bet on the Cambridge biotech’s approach to developing...
Phase I study of CC-90010, a reversible, oral BET inhibitor in patients with advanced solid tumors and relapsed/refractory non-Hodgkin lymphoma.
Related Articles Phase I study of CC-90010, a reversible, oral BET inhibitor in patients with advanced solid tumors and relapsed/refractory non-Hodgkin lymphoma. Ann Oncol. 2020...
BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling
BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling Source link...
Inducing Labor Safer Bet for Late-Term Pregnancies
It’s widely believed that mothers and babies have an increased risk of problems at or beyond 42 weeks of pregnancy. Source link...
Vertex’s next act: a billion-dollar bet on a cure for type 1 diabetes
Vertex Pharmaceuticals announced Tuesday that it plans to acquire an ambitious startup for $950 million, betting the company’s early-stage science could lead to a functional...
BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart.
Related Articles BET Bromodomain Inhibitors and Pulmonary Arterial Hypertension: Take Care of the Heart. Am J Respir Crit Care Med. 2019 Aug 16;: Authors: Piquereau...
Novel phenanthridin-6(5H)-one derivatives as potent and selective BET bromodomain inhibitors: Rational design, synthesis and biological evaluation.
Related Articles Novel phenanthridin-6(5H)-one derivatives as potent and selective BET bromodomain inhibitors: Rational design, synthesis and biological evaluation. Eur J Med Chem. 2019 Jun 28;179:502-514...
Exploiting the 7-methylimidazo[1,5-a]pyrazin-8(7H)-one scaffold for the development of novel chemical inhibitors for Bromodomain and Extraterminal Domain (BET) family.
Related Articles Exploiting the 7-methylimidazo[1,5-a]pyrazin-8(7H)-one scaffold for the development of novel chemical inhibitors for Bromodomain and Extraterminal Domain (BET) family. Bioorg Chem. 2019 Jun 11;90:103044...
Whole-Body MRI: A Better Bet for Lung, Colon Ca Staging?
(MedPage Today) — Streamline trials show faster, less expensive results versus standard imaging Source link...
Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.
Related Articles Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma. Neoplasia. 2019 Feb 20;21(3):322-330 Authors: Choi JE, Verhaegen ME, Yazdani...
Getting Flu Shot During Hospital Stay a Safe Bet
People who received a flu shot while in the hospital had no increased risk of outpatient visits or hospital readmission within seven days after leaving...
Eli Lilly to buy Loxo Oncology for $8 billion in huge bet on cancer genetics
Eli Lilly, the Indianapolis-based drug giant, said Monday that it will purchase Loxo Oncology, a tiny startup, for $8 billion in cash to gain access...