Tag: Autophagic cell death

Biology

Mitotic phosphorylation of the ULK complex regulates cell cycle progression

Newsemia
by Akinori Yamasaki, Yui Jin, Yoshinori Ohsumi Autophagy is an intracellular degradation pathway targeting organelles and macromolecules, thereby regulating various cellular functions. Phosphorylation is a...
Biology

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

Newsemia
by Zhiyuan Li, Xiaofei Tian, Xinmiao Ji, Junjun Wang, Hanxiao Chen, Dongmei Wang, Xin Zhang Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the...
Biology

N-terminal β-strand underpins biochemical specialization of an ATG8 isoform

Newsemia
by Erin K. Zess, Cassandra Jensen, Neftaly Cruz-Mireles, Juan Carlos De la Concepcion, Jan Sklenar, Madlen Stephani, Richard Imre, Elisabeth Roitinger, Richard Hughes, Khaoula Belhaj,...
Biology

Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

Newsemia
by Philipp Kirchner, Mathieu Bourdenx, Julio Madrigal-Matute, Simoni Tiano, Antonio Diaz, Boris A. Bartholdy, Britta Will, Ana Maria Cuervo Chaperone-mediated autophagy (CMA) contributes to the...
Biology

Dhh1 promotes autophagy-related protein translation during nitrogen starvation

Newsemia
by Xu Liu, Zhiyuan Yao, Meiyan Jin, Sim Namkoong, Zhangyuan Yin, Jun Hee Lee, Daniel J. Klionsky Macroautophagy (hereafter autophagy) is a well-conserved cellular process...
Biology

CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor

Newsemia
by Christopher J. Shoemaker, Tina Q. Huang, Nicholas R. Weir, Nicole Polyakov, Sebastian W. Schultz, Vladimir Denic The power of forward genetics in yeast is...
Biology

Differential and convergent utilization of autophagy components by positive-strand RNA viruses

Newsemia
by Emma Abernathy, Roberto Mateo, Karim Majzoub, Nick van Buuren, Sara W. Bird, Jan E. Carette, Karla Kirkegaard Many viruses interface with the autophagy pathway,...

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