Tag: atrophy

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Early pericalcarine atrophy in acute optic neuritis is associated with conversion to multiple sclerosis

Newsemia
Jenkins, TM; Ciccarelli, O; Atzori, M; Wheeler-Kingshott, CAM; Miller, DH; Thompson, AJ; Toosy, AT; (2011) Early pericalcarine atrophy in acute optic neuritis is associated with...
Biology

Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation

Newsemia
by Ying-Qiu Zheng, Yu Zhang, Yvonne Yau, Yahar Zeighami, Kevin Larcher, Bratislav Misic, Alain Dagher It is becoming increasingly clear that brain network organization shapes...
AI/ML

Hippocampal segmentation for brains with extensive atrophy using three-dimensional convolutional neural networks.

Newsemia
Related Articles Hippocampal segmentation for brains with extensive atrophy using three-dimensional convolutional neural networks. Hum Brain Mapp. 2019 Oct 14;: Authors: Goubran M, Ntiri EE,...
Latest News

IVERIC bio’s Zimura®, a Novel Complement C5 Inhibitor, Met its Primary Endpoint and Reached Statistical Significance in a Phase 2b Randomized, Controlled Clinical Trial in Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration

Newsemia
NEW YORK–(BUSINESS WIRE)–IVERIC bio, Inc. announced initial topline data confirming that Zimura® met its prespecified primary endpoint in its Phase 2b clinical trial. Source link...
Neurology

A novel homoplasmic mitochondrial DNA mutation (m.13376T>C, p.I347T) of MELAS presenting characteristic medial temporal lobe atrophy

Newsemia
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is a maternally inherited mitochondrial cytopathy that usually affects people under 40 years of age with variable...
Cardiology

Brain-derived neurotrophic factor mimetic, 7,8-dihydroxyflavone, protects against myocardial ischemia by rebalancing optic atrophy 1 processing.

Newsemia
Brain-derived neurotrophic factor mimetic, 7,8-dihydroxyflavone, protects against myocardial ischemia by rebalancing optic atrophy 1 processing. Free Radic Biol Med. 2019 Sep 28;: Authors: Wang Z,...
Latest News

Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis

Newsemia
Eijlers, AJC; Dekker, I; Steenwijk, MD; Meijer, KA; Hulst, HE; Pouwels, PJW; Uitdehaag, BMJ; … Geurts, JJG; + view all Eijlers, AJC; Dekker, I; Steenwijk,...
Neurology

The facial nerve atrophy with spinal and bulbar muscular atrophy patients (SBMA): Three case reports with 3D fast imaging employing steady-state acquisition (FIESTA)

Newsemia
Spinal and bulbar muscular atrophy (SBMA) is an X-linked neuromuscular disease caused by a CAG repeat expansion in the androgen receptor (AR) gene [1]. Men...
Pharma / Biotech

Vaginal tamoxifen for treatment of vulvar and vaginal atrophy: Pharmacokinetics and local tolerance in a rabbit model over 28 days.

Newsemia
Related Articles Vaginal tamoxifen for treatment of vulvar and vaginal atrophy: Pharmacokinetics and local tolerance in a rabbit model over 28 days. Int J Pharm....

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