apoptosis

Corrigendum to “Neuroprotective effect of nicorandil through inhibition of apoptosis by the PI3K/Akt1 pathway in a mouse model of deep hypothermic low flow” [Journal of the Neurological Sciences Volume 357, Issues 1–2, 15 October 2015, Pages 119–125]

The authors regret Dr. Kejie Yin is not an author of this publication. Source link

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Small molecule drug could be an effective strategy to treat glioblastoma

A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to...

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Marine natural compounds could be potential treatments for triple negative breast cancer

[ad_1] The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products. Source link [ad_2]

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Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

by Hannah Grace Roddie, Emma Louise Armitage, Jonathon Alexis Coates, Simon Andrew Johnston, Iwan Robert Evans Macrophages encounter and clear apoptotic cells during normal development and homeostasis, including at numerous...

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Scientific research articles show that imipridones target mitochondrial function in cancer cells

[ad_1] Oncoceutics, Inc. announced the publication of two scientific research articles demonstrating that members of the imipridone family ONC201 and ONC212 directly activate a mitochondrial protease called caseinolytic protease P....

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Scientists discover biological barrier that keeps cancer at bay

[ad_1] Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and...

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Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance [Research Article]

Protein degradation pathways are critical for maintaining proper protein dynamics within the cell, and considerable efforts have been made toward the development of therapeutics targeting these catabolic processes. We report...

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Epigallocatechin gallate prevents mitochondrial impairment and cell apoptosis by regulating miR-30a/p53 axis.

[ad_1] Related Articles Epigallocatechin gallate prevents mitochondrial impairment and cell apoptosis by regulating miR-30a/p53 axis. Phytomedicine. 2019 Jan 30;61:152845 Authors: Zhang C, Liao P, Liang R, Zheng X, Jian J...

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A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells

The post A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells appeared first on Biochemistry Blog: Biochemistry Help. Source link

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PM2.5-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway.

[ad_1] Related Articles PM2.5-induced ADRB2 hypermethylation contributed to cardiac dysfunction through cardiomyocytes apoptosis via PI3K/Akt pathway. Environ Int. 2019 Apr 12;127:601-614 Authors: Yang X, Zhao T, Feng L, Shi Y,...

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‘Hit-and-run’ interaction between proteins appears to be key trigger for cell death

[ad_1] A 'hit-and-run' interaction between two proteins could be an important trigger for cell death, according to new research from Walter and Eliza Hall Institute researchers. Source link [ad_2]

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Nobiletin suppresses oxidative stress and apoptosis in H9c2 cardiomyocytes following hypoxia/reoxygenation injury.

[ad_1] Nobiletin suppresses oxidative stress and apoptosis in H9c2 cardiomyocytes following hypoxia/reoxygenation injury. Eur J Pharmacol. 2019 Apr 02;: Authors: Liu F, Zhang H, Li Y, Lu X Abstract Nobiletin...

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Researchers identify a more effective treatment for cancer

[ad_1] Researchers from Mount Sinai and IBM have discovered a novel clue in explaining how cancer cells with identical genomes can respond differently to the same therapy. Source link [ad_1]

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Long noncoding RNA UCA1 inhibits ischaemia/reperfusion injury induced cardiomyocytes apoptosis via suppression of endoplasmic reticulum stress.

[ad_1] Related Articles Long noncoding RNA UCA1 inhibits ischaemia/reperfusion injury induced cardiomyocytes apoptosis via suppression of endoplasmic reticulum stress. Genes Genomics. 2019 Mar 15;: Authors: Chen J, Hu Q, Zhang...

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Researchers identify new diagnostic clues for life-limiting lung condition

[ad_1] A new biomarker that could be used to provide earlier diagnosis for a life-limiting lung condition has been identified by researchers at the University of Bradford. Source link [ad_2]

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Exosomes of bone-marrow stromal cells inhibit cardiomyocyte apoptosis under ischemic and hypoxic conditions via miR-486-5p targeting the PTEN/PI3K/AKT signaling pathway.

[ad_1] Related Articles Exosomes of bone-marrow stromal cells inhibit cardiomyocyte apoptosis under ischemic and hypoxic conditions via miR-486-5p targeting the PTEN/PI3K/AKT signaling pathway. Thromb Res. 2019 Feb 02;177:23-32 Authors: Sun...

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Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis

[ad_1] Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis Source link [ad_1]

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New technology platform digitally counts growth factors in single cells

[ad_1] Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors...

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Induced aneuploidy in neural stem cells triggers a delayed stress response and impairs adult life span in flies

[ad_1] by Mihailo Mirkovic, Leonardo G. Guilgur, Alexandra Tavares, Diogo Passagem-Santos, Raquel A. Oliveira Studying aneuploidy during organism development has strong limitations because chronic mitotic perturbations used to generate aneuploidy...

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In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose

[ad_1] The post In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose appeared first on Biochemistry Blog: Biochemistry Help....

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