apoptosis

How cell-free DNA can be targeted to prevent spread of tumors

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. Source link

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Muscular apoptosis but not oxidative stress increases with old age in a long-lived diver, the Weddell seal [RESEARCH ARTICLE]

Kaitlin N. Allen, Jose Pablo Vazquez-Medina, John M. Lawler, Jo-Ann E. Mellish, Markus Horning, and Allyson G. Hindle Seals experience repeated bouts of ischemia–reperfusion while diving, potentially exposing their tissues...

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Asprosin improves the survival of mesenchymal stromal cells in myocardial infarction by inhibiting apoptosis via the activated ERK1/2-SOD2 pathway.

Asprosin improves the survival of mesenchymal stromal cells in myocardial infarction by inhibiting apoptosis via the activated ERK1/2-SOD2 pathway. Life Sci. 2019 Jun 10;:116554 Authors: Zhang Z, Tan Y, Zhu...

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Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis

Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis Source link

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Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation Source link

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Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1

by Tong Liu, Tomomi Kuwana, Hongkai Zhang, Matthew G. Vander Heiden, Richard A. Lerner, Donald D. Newmeyer Bcl-2 family proteins control a decisive apoptotic event: mitochondrial outer membrane permeabilization (MOMP)....

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Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway

Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway Source link

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Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor...

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Muscular apoptosis but not oxidative stress increases with old age in a long-lived diver, the Weddell seal [RESEARCH ARTICLE]

Kaitlin N. Allen, Jose Pablo Vazquez-Medina, John M. Lawler, Jo-Ann E. Mellish, Markus Horning, and Allyson G. HindleSeals experience repeated bouts of ischemia-reperfusion while diving, potentially exposing their tissues to...

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Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression

Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression Source link

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KPC1 alleviates hypoxia/reoxygenation-induced apoptosis in rat cardiomyocyte cells though BAX degradation.

Related Articles KPC1 alleviates hypoxia/reoxygenation-induced apoptosis in rat cardiomyocyte cells though BAX degradation. J Cell Physiol. 2019 May 30;: Authors: Yuan Y, Wang YY, Liu X, Luo B, Zhang L,...

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Corrigendum to “Neuroprotective effect of nicorandil through inhibition of apoptosis by the PI3K/Akt1 pathway in a mouse model of deep hypothermic low flow” [Journal of the Neurological Sciences Volume 357, Issues 1–2, 15 October 2015, Pages 119–125]

The authors regret Dr. Kejie Yin is not an author of this publication. Source link

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Small molecule drug could be an effective strategy to treat glioblastoma

A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to...

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Marine natural compounds could be potential treatments for triple negative breast cancer

[ad_1] The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products. Source link [ad_2]

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Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

by Hannah Grace Roddie, Emma Louise Armitage, Jonathon Alexis Coates, Simon Andrew Johnston, Iwan Robert Evans Macrophages encounter and clear apoptotic cells during normal development and homeostasis, including at numerous...

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Scientific research articles show that imipridones target mitochondrial function in cancer cells

[ad_1] Oncoceutics, Inc. announced the publication of two scientific research articles demonstrating that members of the imipridone family ONC201 and ONC212 directly activate a mitochondrial protease called caseinolytic protease P....

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Scientists discover biological barrier that keeps cancer at bay

[ad_1] Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and...

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Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance [Research Article]

Protein degradation pathways are critical for maintaining proper protein dynamics within the cell, and considerable efforts have been made toward the development of therapeutics targeting these catabolic processes. We report...

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Epigallocatechin gallate prevents mitochondrial impairment and cell apoptosis by regulating miR-30a/p53 axis.

[ad_1] Related Articles Epigallocatechin gallate prevents mitochondrial impairment and cell apoptosis by regulating miR-30a/p53 axis. Phytomedicine. 2019 Jan 30;61:152845 Authors: Zhang C, Liao P, Liang R, Zheng X, Jian J...

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A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells

The post A novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells appeared first on Biochemistry Blog: Biochemistry Help. Source link

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