apoptosis

Physical activity may attenuate unfavorable atherogenic changes in menopausal women

A new study on menopausal women shows that leisure-time physical activity is associated with a healthier blood lipid profile. However, results suggest that leisure-time physical activity does not seem to...

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Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway.

Related Articles Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3657-3663 Authors: Yu H, Chen B, Ren Q Abstract Background: Myocardial ischemia...

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KAIST researchers describe new mechanism that induces self-killing of cancer cells

Researchers have described a new mechanism which induces the self-killing of cancer cells by perturbing ion homeostasis. A research team from the Department of Biochemical Engineering has developed helical polypeptide...

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BRAFV600E-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts

BRAFV600E-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts Source link

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Optineurin downregulation induces endoplasmic reticulum stress, chaperone-mediated autophagy, and apoptosis in pancreatic cancer cells

Optineurin downregulation induces endoplasmic reticulum stress, chaperone-mediated autophagy, and apoptosis in pancreatic cancer cells Source link

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Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression

Epithelial tight junctions are compromised in patients with gastrointestinal disease. Occludin is a protein component of tight junctions; its removal from tight junctions or reduced expression results in barrier loss....

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CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263

CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263 Source link

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Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells.

Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells. Int J Biochem Cell Biol. 2019 Jul 17;:105573 Authors: Dong X, Zhao R, Li...

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How cell-free DNA can be targeted to prevent spread of tumors

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. Source link

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Muscular apoptosis but not oxidative stress increases with old age in a long-lived diver, the Weddell seal [RESEARCH ARTICLE]

Kaitlin N. Allen, Jose Pablo Vazquez-Medina, John M. Lawler, Jo-Ann E. Mellish, Markus Horning, and Allyson G. Hindle Seals experience repeated bouts of ischemia–reperfusion while diving, potentially exposing their tissues...

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Asprosin improves the survival of mesenchymal stromal cells in myocardial infarction by inhibiting apoptosis via the activated ERK1/2-SOD2 pathway.

Asprosin improves the survival of mesenchymal stromal cells in myocardial infarction by inhibiting apoptosis via the activated ERK1/2-SOD2 pathway. Life Sci. 2019 Jun 10;:116554 Authors: Zhang Z, Tan Y, Zhu...

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Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis

Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis Source link

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Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation Source link

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Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1

by Tong Liu, Tomomi Kuwana, Hongkai Zhang, Matthew G. Vander Heiden, Richard A. Lerner, Donald D. Newmeyer Bcl-2 family proteins control a decisive apoptotic event: mitochondrial outer membrane permeabilization (MOMP)....

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Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway

Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway Source link

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Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor...

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Muscular apoptosis but not oxidative stress increases with old age in a long-lived diver, the Weddell seal [RESEARCH ARTICLE]

Kaitlin N. Allen, Jose Pablo Vazquez-Medina, John M. Lawler, Jo-Ann E. Mellish, Markus Horning, and Allyson G. HindleSeals experience repeated bouts of ischemia-reperfusion while diving, potentially exposing their tissues to...

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Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression

Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression Source link

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KPC1 alleviates hypoxia/reoxygenation-induced apoptosis in rat cardiomyocyte cells though BAX degradation.

Related Articles KPC1 alleviates hypoxia/reoxygenation-induced apoptosis in rat cardiomyocyte cells though BAX degradation. J Cell Physiol. 2019 May 30;: Authors: Yuan Y, Wang YY, Liu X, Luo B, Zhang L,...

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Corrigendum to “Neuroprotective effect of nicorandil through inhibition of apoptosis by the PI3K/Akt1 pathway in a mouse model of deep hypothermic low flow” [Journal of the Neurological Sciences Volume 357, Issues 1–2, 15 October 2015, Pages 119–125]

The authors regret Dr. Kejie Yin is not an author of this publication. Source link

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