Tag : AntiTumor

Dermatology

Interaction of C20-substituted derivative of pregnenolone acetate with copper (II) leads to ROS generation, DNA cleavage and apoptosis in cervical cancer cells: Therapeutic potential of copper chelation for cancer treatment.

Newsemia
Related Articles Interaction of C20-substituted derivative of pregnenolone acetate with copper (II) leads to ROS generation, DNA cleavage and apoptosis in cervical cancer cells: Therapeutic...
Pharma / Biotech

Multifunctional nanoparticles from albumin for stimuli-responsive efficient dual drug delivery.

Newsemia
Related Articles Multifunctional nanoparticles from albumin for stimuli-responsive efficient dual drug delivery. Bioorg Chem. 2019 07;88:102959 Authors: Nosrati H, Abhari F, Charmi J, Davaran S,...
Pharma / Biotech

ZnAs@SiO2 nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma via SHP-1/JAK2/STAT3 signaling.

Newsemia
Related Articles ZnAs@SiO2 nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma via SHP-1/JAK2/STAT3 signaling. Theranostics. 2019;9(15):4391-4408 Authors: Huang...
Gastroenterology

Real-world clinical effectiveness and safety of vedolizumab and anti-tumor necrosis factor alpha treatment in ulcerative colitis and Crohn’s disease patients: a German retrospective chart review

Newsemia
Real-world comparisons of biologic treatment outcomes for ulcerative colitis (UC) or Crohn’s disease (CD) patients are limited. We sought to evaluate the real-world effectiveness of...
Latest News

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Newsemia
A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable...
Latest News

Initial Results from MOUNTAINEER Trial Show Antitumor Activity of Tucatinib Combination in HER2-Positive Metastatic Colorectal Cancer

Newsemia
BARCELONA, Spain–(BUSINESS WIRE)–Seattle Genetics, Inc. (Nasdaq:SGEN) today announced that initial data were presented from the single arm phase 2 clinical trial known as MOUNTAINEER. The...

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