Tag : Antineoplastic Agents / therapeutic use

Pharma / Biotech

Preparation of high drug-loading celastrol nanosuspensions and their anti-breast cancer activities in vitro and in vivo.

Newsemia
Related Articles Preparation of high drug-loading celastrol nanosuspensions and their anti-breast cancer activities in vitro and in vivo. Sci Rep. 2020 06 01;10(1):8851 Authors: Huang...
Pharma / Biotech

Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C.

Newsemia
Related Articles Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C. J Med Chem. 2020 05 14;63(9):4468-4483 Authors: Kettle JG,...
Pharma / Biotech

Doxorubicin-loading core-shell pectin nanocell: A novel nanovehicle for anticancer agent delivery with multidrug resistance reversal.

Newsemia
Related Articles Doxorubicin-loading core-shell pectin nanocell: A novel nanovehicle for anticancer agent delivery with multidrug resistance reversal. PLoS One. 2020;15(6):e0235090 Authors: Ouyang J, Yang M,...
Pharma / Biotech

Hyaluronic acid modified doxorubicin loaded Fe3O4 nanoparticles effectively inhibit breast cancer metastasis.

Newsemia
Related Articles Hyaluronic acid modified doxorubicin loaded Fe3O4 nanoparticles effectively inhibit breast cancer metastasis. J Mater Chem B. 2019 10 14;7(38):5861-5872 Authors: Gong T, Dong...
Dentistry

A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition.

Newsemia
Related Articles A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition. Cancer Res. 2020 02 15;80(4):757-770 Authors: Kitchen P, Lee KY,...
Pharma / Biotech

Does Industry-Conducted All-Case Surveillance of Newly Approved Oncology Drugs Contribute to the Revision of Package Inserts in Japan?

Newsemia
Related Articles Does Industry-Conducted All-Case Surveillance of Newly Approved Oncology Drugs Contribute to the Revision of Package Inserts in Japan? Clin Transl Sci. 2019 09;12(5):505-512...
Cardiology

Long-Term Outcome of WHIM Syndrome in 18 Patients: High Risk of Lung Disease and HPV-Related Malignancies.

Newsemia
Related Articles Long-Term Outcome of WHIM Syndrome in 18 Patients: High Risk of Lung Disease and HPV-Related Malignancies. J Allergy Clin Immunol Pract. 2019 May...

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