Tag : Antineoplastic Agents / pharmacokinetics

Pharma / Biotech

A MSN-based tumor-targeted nanoplatform to interfere with lactate metabolism to induce tumor cell acidosis for tumor suppression and anti-metastasis.

Newsemia
Related Articles A MSN-based tumor-targeted nanoplatform to interfere with lactate metabolism to induce tumor cell acidosis for tumor suppression and anti-metastasis. Nanoscale. 2020 Feb 07;12(5):2966-2972...
Pharma / Biotech

Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C.

Newsemia
Related Articles Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C. J Med Chem. 2020 05 14;63(9):4468-4483 Authors: Kettle JG,...
Pharma / Biotech

Biodegradable Polymeric Multilayer Capsules for Therapy of Lung Cancer.

Newsemia
Related Articles Biodegradable Polymeric Multilayer Capsules for Therapy of Lung Cancer. ACS Appl Mater Interfaces. 2020 Feb 05;12(5):5610-5623 Authors: Novoselova MV, Loh HM, Trushina DB,...
Pharma / Biotech

Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles.

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Related Articles Enhancing Tumor Drug Distribution With Ultrasound-Triggered Nanobubbles. J Pharm Sci. 2019 09;108(9):3091-3098 Authors: Nittayacharn P, Yuan HX, Hernandez C, Bielecki P, Zhou H,...
Pharma / Biotech

New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments.

Newsemia
Related Articles New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments. Theranostics. 2019;9(18):5332-5346 Authors:...

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