Antibiotic Resistance

Decreasing inappropriate antibiotic use is key strategy to control drug resistance

Antibiotic resistance is a larger public health threat than most people realize. And, the Centers for Disease Control and Prevention reports about half of all antibiotics in outpatient settings are...

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Antibiotics face an existential crisis

Antibiotics are facing an existential crisis less than a century after their introduction. The bacteria-fighting drugs are becoming less effective as a result of their overuse in both humans and...

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Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics

by Allison L. Hicks, Stephen M. Kissler, Marc Lipsitch, Yonatan H. Grad The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect...

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Good news, bad news: lower antibiotic use, more antibiotic resistance in UK

Public Health England (PHE) is cheering about a significant fall in the number of antibiotic prescriptions in England over the five years between 2014 and 2019, when it has dropped...

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Mechanism for antibiotic resistance in Pseudomonas explained in new research

A new study has revealed the underlying mechanism of development of antibiotic resistance among Pseudomonas aeruginosa (P. aeruginosa). Pseudomonas is known to cause severe and often life threatening infections in...

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Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance

by Jeff Maltas, Kevin B. Wood Evolved resistance to one antibiotic may be associated with "collateral" sensitivity to other drugs. Here, we provide an extensive quantitative characterization of collateral effects...

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Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection

by Kyle J. Card, Thomas LaBar, Jasper B. Gomez, Richard E. Lenski Populations often encounter changed environments that remove selection for the maintenance of particular phenotypic traits. The resulting genetic...

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Half the drugs in use damage gut bacteria, says new study

A startling presentation at UEG Week 2019, in Barcelona, reveals that the gut microbiome is at high risk for damage each time we use a drug from one or more...

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Antibiotic resistance doubles in just two decades

Antibiotic resistance poses a grave challenge to many previously curable infectious diseases. At present, antibiotic resistance is proving to increase at a much faster rate compared to the development of...

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Antibiotic Resistance Now Affects More Food Animals, Increases Disease Risk

A new study found that antibiotic resistance now affects more animals in many countries, which may contribute to a large-scale food supply problem. Source link

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Antibiotic resistance is transferring from humans to animals

Resistance to antibiotics could be moving from humans to animals, research by a Clemson University professor has shown. The research details results that demonstrate reverse zoonosis, a process by which...

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Long-term antibiotic use in preemies promotes drug-resistant gut bacteria

Very preterm infants are often sick and require antibiotic treatment to save their lives. However, when this form of therapy lasts for 20 months or more, it may affect the...

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Thames typical of superbug-breeding rivers, says new study

The River Thames is rapidly becoming a breeding pool for antibiotic-resistant bacteria, according to a new study, which underlines the urgent need to cut down the amount of antibiotics currently...

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Scientists discover how resistant bacteria block entrance of antibiotics

Scientists have discovered how Klebsiella pneumoniae evolves to become resistant to carbapenem antibiotics. Source link

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Scientists find a potent weapon against antibiotic resistance

Antibiotic resistance is a big threat to global health, and a growing number of infections are now becoming harder to treat. The usual treatments, like antibiotics used to treat them,...

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Powerful weapon discovered to fight antibiotic resistance in Staphylococcus aureus

Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to...

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Two New Resistance-Proof Antibiotics Have Been Created

Antibiotic resistance is a growing global concern. Two new resistance-proof antibiotics have been created at the Inserm and Université de Rennes 1. Source link

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Researchers reveal virulence regulatory mechanism in a superbug

As antibiotic resistance is growing and posing a threat on public health, developing new antibiotics has become more urgent than ever. Source link

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Harnessing robotic automation and web-based technologies to modernize scientific outreach

by Orna Dahan, Bat-Shahar Dorfman, Serkan Sayin, Brittany Rosener, Tiffany Hua, Anat Yarden, Amir Mitchell Technological breakthroughs in the past two decades have ushered in a new era of biomedical...

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Plant foods may transmit antibiotic-resistant superbugs to humans

Researchers have revealed that plant foods may be transmitting antibiotic resistance to the gut microbiome. Source link

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