Tag : angiotensin

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Genetic variants of human ACE2 are differentially recognized by SARS-CoV-2

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Scientists at the University of Wisconsin reveals that the genetic variants of human angiotensin 2 (ACE2) receptors can have altered recognition by severe acute respiratory...
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Adaptations found in RNA secondary structure in genes of two proteins of SARS-CoV-2

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To investigate mutations in coronaviruses, a new study by scientists at Duke University and published on the preprint server bioRxiv, used a computational methodology, adaptiPhy,...
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Researchers develop non-infectious nanoparticle probes to study SARS-CoV-2

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Scientists and researchers at the U.S. Naval Research Laboratory and National Center for Advancing Translational Sciences, submitted their findings to ACS Nano, a monthly peer-reviewed...
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Key China COVID-19 study produced results that influenced subsequent research on coronavirus

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Early in the onset of the COVID-19 pandemic, a small study in China produced results that influenced subsequent research on the virus. Source link...
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S-pseudotyped VLPs offer promising COVID-19 vaccine platform

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A new study published on the preprint server bioRxiv* in September 2020 reports on a Moloney murine leukemia virus (MLV) platform that produces VLPs expressing...
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Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

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In a study published in the preprint server bioRxiv, researchers from the Kyoto Prefectural University of Medicine and Osaka University Japan, discuss how they engineered...
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Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

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After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use...
Cardiology

Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers in hypertensive patients with myocardial infarction or heart failure: a systematic review and meta-analysis.

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Related Articles Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers in hypertensive patients with myocardial infarction or heart failure: a systematic review and meta-analysis. Hypertens Res....
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Single-molecule imaging of SARS-CoV-2 spikes on virus particles

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Using single-molecule FRET analysis, a team of researchers has revealed how the different conformations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein...
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Brain inflammation seen in fatal COVID-19 cases

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Now, a new study by researchers at the Barts Health NHS Trust and the University of Cambridge in the United Kingdom shows that some patients...
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Host gene editing main driving force of SARS-CoV-2 mutations

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A new study published on the aRxiv preprint server in September 2020 shows that the host immune response, mediated by two RNA editors, causes the...
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D614G spike mutation increases infectivity of SARS-CoV-2 and neutralization susceptibility

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As the COVID-19 pandemic progresses, it is crucial to track the viral changes in order to link the clinical and epidemiological features of the disease...
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Spike-based priming leads to high neutralizing activity in animal models

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A new report by researchers at the University of Melbourne and published on the preprint server bioRxiv in September 2020 reports on the use of...
Cardiology

Angiotensin II for Critically Ill Patients With Shock After Heart Transplant.

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Related Articles Angiotensin II for Critically Ill Patients With Shock After Heart Transplant. J Cardiothorac Vasc Anesth. 2020 Aug 07;: Authors: Cutler NS, Rasmussen BM,...
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ACE2/TMPRSS2 not expressed in pancreatic islet endocrine cells

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A new study by researchers at the Vanderbilt University Medical Center and the University of Pennsylvania Perelman School of Medicine and published on the preprint...
Cardiology

Effect of Angiotensin System Inhibitors on Physical Performance in Older People – A Systematic Review and Meta-Analysis.

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Related Articles Effect of Angiotensin System Inhibitors on Physical Performance in Older People – A Systematic Review and Meta-Analysis. J Am Med Dir Assoc. 2020...
Neurology

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

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A study of a gateway receptor for SARS-CoV-2 led by Walter Lukiw, PhD, Professor of Neuroscience, Neurology and Ophthalmology at LSU Health New Orleans’ Neuroscience...
Cardiology

A current review of COVID-19 for the cardiovascular specialist.

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Related Articles A current review of COVID-19 for the cardiovascular specialist. Am Heart J. 2020 08;226:29-44 Authors: Lang JP, Wang X, Moura FA, Siddiqi HK,...

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