Tag : Allosteric

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Cerevel Therapeutics Announces Phase 1 Results for CVL-865, a Novel α2/3/5-subtype GABAA Positive Allosteric Modulator in Development to Treat Epilepsy

Newsemia
BOSTON–(BUSINESS WIRE)–Cerevel Therapeutics, a company dedicated to unraveling the mysteries of the brain to treat neuroscience diseases, announced today results of a Phase 1 dose-escalation...
Biology

Allosteric regulation of a prokaryotic small Ras-like GTPase contributes to cell polarity oscillations in bacterial motility

Newsemia
by Jyoti Baranwal, Sébastien Lhospice, Manil Kanade, Sukanya Chakraborty, Priyanka Rajendra Gade, Shrikant Harne, Julien Herrou, Tâm Mignot, Pananghat Gayathri Mutual gliding motility A (MglA),...
Pharma / Biotech

Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels.

Newsemia
Related Articles Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels. Cell Calcium. 2018 Dec 21;78:26-34 Authors: Häfner...
Neurology

WITHDRAWN: Therapeutic potential of metabotropic glutamate receptor 4-positive allosteric modulator TAS-4 in rodent models of movement disorders

Newsemia
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy...

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