Tag: Aggregates

Neurology

Increased intra-mitochondrial lipofuscin aggregates with spherical dense body formation in mitochondrial myopathy

Newsemia
Lipofuscin aggregation may result from incomplete degradation of damaged mitochondria by autophagy-lysosome pathway, and intra-mitochondrial lipofuscin aggregation may exacerbate mitochondrial abnormalities in mitochondrial myopathy (MM)...
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Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates

Newsemia
Ling, H; Gelpi, E; Davey, K; Jaunmuktane, Z; Mok, KY; Jabbari, E; Simone, R; … Revesz, T; + view all Ling, H; Gelpi, E; Davey,...
Gastroenterology

GLI1 activation by non-classical pathway integrin αvβ3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis

Newsemia
GLI1 activation by non-classical pathway integrin αvβ3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis Source link...
Biology

Human DnaJB6 Antiamyloid Chaperone Protects Yeast from Polyglutamine Toxicity Separately from Spatial Segregation of Aggregates [Research Article]

Newsemia
Polyglutamine (polyQ) aggregates are associated with pathology in protein-folding diseases and with toxicity in the yeast Saccharomyces cerevisiae. Protection from polyQ toxicity in yeast by...
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Relative distance between tracers as a measure of diffusivity within moving aggregates

Newsemia
Poenisch, W; Zaburdaev, V; (2018) Relative distance between tracers as a measure of diffusivity within moving aggregates. The European Physical Journal B , 91 ,...
Biology

Protein aggregates encode epigenetic memory of stressful encounters in individual <i>Escherichia coli</i> cells

Newsemia
by Sander K. Govers, Julien Mortier, Antoine Adam, Abram Aertsen Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a...
Biology

Protein aggregates encode epigenetic memory of stressful encounters in individual <i>Escherichia coli</i> cells

Newsemia
by Sander K. Govers, Julien Mortier, Antoine Adam, Abram Aertsen Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a...
Gastroenterology

The PPARα Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity

Newsemia
The PPARα Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity Source link...

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