Tag : adhesion

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Regulation of cell-cell adhesion in keratinocytes: The reciprocal relationship between cadherins and Rho family GTPases

Newsemia
Betson, Martha Elizabeth; (2001) Regulation of cell-cell adhesion in keratinocytes: The reciprocal relationship between cadherins and Rho family GTPases. Doctoral thesis (Ph.D), UCL (University College...
Gastroenterology

Baseline levels of dynamic CD4+ T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study

Newsemia
While the number of therapeutic options for treating inflammatory bowel diseases (IBD) is increasing, evidence for rational treatment decisions is scarce in many cases. In...
Gastroenterology

P069 ONTAMALIMAB, A FULLY HUMAN MONOCLONAL ANTIBODY AGAINST MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1, PROVIDES SUSTAINED EXPOSURE FOLLOWING LONG-TERM TREATMENT IN PATIENTS WITH ULCERATIVE COLITIS

Newsemia
Ontamalimab is a fully human immunoglobulin G2 monoclonal antibody against mucosal addressin cell adhesion molecule-1 in development for the induction and maintenance of clinical remission...
Biology

Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion [Research Article]

Newsemia
Cyclase-associated protein 1 (CAP1) is a conserved actin-regulating protein that enhances actin filament dynamics and also regulates adhesion in mammalian cells. We previously found that...
Latest News

Using Nanotechnology to Improve Soft Tissue Adhesion to Intraosseous Transcutaneous Amputation Prostheses (ITAP)

Newsemia
Giusto, Elena; (2019) Using Nanotechnology to Improve Soft Tissue Adhesion to Intraosseous Transcutaneous Amputation Prostheses (ITAP). Doctoral thesis (Ph.D), UCL (University College London). Source link...
Biology

The tricellular vertex-specific adhesion molecule Sidekick facilitates polarised cell intercalation during <i>Drosophila</i> axis extension

Newsemia
by Tara M. Finegan, Nathan Hervieux, Alexander Nestor-Bergmann, Alexander G. Fletcher, Guy B. Blanchard, Bénédicte Sanson In epithelia, tricellular vertices are emerging as important sites...
Gastroenterology

Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target

Newsemia
Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target Source link...
Gastroenterology

Adhesion reformation and the limited translational value of experiments with adhesion barriers: A systematic review and meta-analysis of animal models

Newsemia
Adhesion reformation and the limited translational value of experiments with adhesion barriers: A systematic review and meta-analysis of animal models Source link...
Latest News

Protein implicated in neuron growth and cell adhesion appears crucial for pain sensitization

Newsemia
Researchers from Japan’s Osaka University have made an important leap in our understanding of how chronic pain conditions develop. Source link...
Biology

Diversification of the type IV filament superfamily into machines for adhesion, protein secretion, DNA uptake, and motility

Newsemia
by Rémi Denise, Sophie S. Abby, Eduardo P. C. Rocha Processes of molecular innovation require tinkering and shifting in the function of existing genes. How...

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