adenocarcinoma – Newsemia

Diagnosis of vascular invasion in pancreatic ductal adenocarcinoma using endoscopic ultrasound elastography

NewsemiaMarch 31, 2020

by NewsemiaMarch 31, 2020023

Vascular invasion is an important criterion for resectability and deciding the therapeutic strategy for pancreatic ductal adenocarcinoma (PDAC), but imaging diagnosis is currently difficult. Endoscopic...

Gastroenterology

Carcinogenesis of Pancreatic Ductal Adenocarcinoma

NewsemiaMarch 19, 2020

by NewsemiaMarch 19, 202002

Although the estimated time for development of pancreatic ductal adenocarcinoma (PDA) is more than 20 years, PDAs are usually detected at late, metastatic stages. PDAs...

Gastroenterology

Correction: PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability

NewsemiaMarch 4, 2020

by NewsemiaMarch 4, 2020039

Correction: PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability Source link...

Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma

NewsemiaFebruary 17, 2020

by NewsemiaFebruary 17, 2020030

Noorani, A; Li, X; Goddard, M; Crawte, J; Alexandrov, LB; Secrier, M; Eldridge, MD; … Fitzgerald, RC; + view all Noorani, A; Li, X; Goddard,...

Gastroenterology

TG01/GM-CSF and adjuvant gemcitabine in patients with resected RAS-mutant adenocarcinoma of the pancreas (CT TG01-01): a single-arm, phase 1/2 trial

NewsemiaFebruary 17, 2020

by NewsemiaFebruary 17, 2020040

TG01/GM-CSF and adjuvant gemcitabine in patients with resected RAS-mutant adenocarcinoma of the pancreas (CT TG01-01): a single-arm, phase 1/2 trial Source link...

Gastroenterology

Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels

NewsemiaFebruary 15, 2020

by NewsemiaFebruary 15, 2020040

Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels Source link...

Gastroenterology

BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma

NewsemiaFebruary 10, 2020

by NewsemiaFebruary 10, 2020034

BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma Source link...

Gastroenterology

Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data

NewsemiaFebruary 5, 2020

by NewsemiaFebruary 5, 2020049

Esophageal adenocarcinomas (EAC) are heterogeneous and often preceded by Barrett’s esophagus (BE). Many genomic changes have been associated with development of BE and EAC, but...

Gastroenterology

VGLL3 is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in stomach adenocarcinoma

NewsemiaFebruary 4, 2020

by NewsemiaFebruary 4, 2020031

VGLL3 is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in stomach adenocarcinoma Source link...

Gastroenterology

KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion

NewsemiaFebruary 3, 2020

by NewsemiaFebruary 3, 202007

KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion Source link...

Gastroenterology

A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma

NewsemiaJanuary 15, 2020

by NewsemiaJanuary 15, 2020016

A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma Source link...

Gastroenterology

Early VTE linked with worse survival in pancreatic ductal adenocarcinoma

NewsemiaJanuary 3, 2020

by NewsemiaJanuary 3, 2020017

Frequent and early onset of venous thromboembolism are associated with decreased progression-free survival and overall survival among patients diagnosed with pancreatic ductal adenocarcinoma, according to...

Gastroenterology

Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma

NewsemiaDecember 23, 2019

by NewsemiaDecember 23, 201905

Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma Source link...

Brain tumor 'GPS' maps soon be tested in clinical trials

NewsemiaDecember 22, 2019

by NewsemiaDecember 22, 201902

A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors...

Gastroenterology

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma

NewsemiaDecember 20, 2019

by NewsemiaDecember 20, 201902

Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma Source link...

Gastroenterology

Ultrasound-induced Cavitation enhances the efficacy of Chemotherapy in a 3D Model of Pancreatic Ductal Adenocarcinoma with its microenvironment

NewsemiaDecember 15, 2019

by NewsemiaDecember 15, 201903

Ultrasound-induced Cavitation enhances the efficacy of Chemotherapy in a 3D Model of Pancreatic Ductal Adenocarcinoma with its microenvironment Source link...

Gastroenterology

Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target

NewsemiaDecember 8, 2019

by NewsemiaDecember 8, 201902

Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target Source link...

Gastroenterology

Correction: A qualitative transcriptional signature for determining the grade of colorectal adenocarcinoma

NewsemiaDecember 5, 2019

by NewsemiaDecember 5, 201903

Correction: A qualitative transcriptional signature for determining the grade of colorectal adenocarcinoma Source link...

Gastroenterology

Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation

NewsemiaDecember 2, 2019

by NewsemiaDecember 2, 201904

Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation Source link...

Gastroenterology

Diphenylbutylpiperidine Antipsychotic Drugs Inhibit Prolactin Receptor Signaling to Reduce Growth of Pancreatic Ductal Adenocarcinoma in Mice

NewsemiaNovember 29, 2019

by NewsemiaNovember 29, 201903

Prolactin (PRL) signaling is upregulated in hormone-responsive cancers. The PRL receptor (PRLR) is class I cytokine receptor that signals via the JAK–STAT and MAPK pathways...