adenocarcinoma

Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer

A clinical trial testing the toxicity of a KRAS inhibitor demonstrated early promising antitumor activity and few adverse side effects in patients with advanced non-small cell lung cancer harboring KRAS...

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Updated ASGE guideline on screening and surveillance of Barrett's esophagus released

The American Society for Gastrointestinal Endoscopy has released its updated "ASGE guideline on screening and surveillance of Barrett's esophagus," published in the September issue of GIE: Gastrointestinal Endoscopy. Source link

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Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma

Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma Source link

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Nerve cells aid in the spread of pancreatic cancer, study reveals

A couple of molecules that nerve cells use to grow during development could help explain why the most common pancreatic cancers are so difficult to contain and for patients to...

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The Metabolic Time Line of Pancreatic Cancer: Opportunities to Improve Early Detection of Adenocarcinoma

A reliable biomarker to detect pancreatic ductal adenocarcinoma (PDAC) continues to be elusive. With employing metabolomics we hypothesize that a broader analysis of systemic blood can differentiate different stages of...

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Researchers decode chain of molecules critical for growth and survival of pancreatic cancer

Researchers at Georgetown Lombardi Comprehensive Cancer Center have decoded a chain of molecules that are critical for the growth and survival of pancreatic ductal adenocarcinoma (PDAC)-;the most common and also...

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Drug that treat human breast cancer might also work for canine lung cancer

Despite those velvet paintings of poker-playing dogs smoking pipes, cigars and cigarettes, our canine friends really don't use tobacco. But like many humans who have never smoked, dogs still get...

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Author Correction: Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma

Author Correction: Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma Source link

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Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma

Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma Source link

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TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma

TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma Source link

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Discovery of distinct lung cancer pathways could help future patients

Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Source link

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Role of Right Hemicolectomy in Patients with Low-Grade Appendiceal Mucinous Adenocarcinoma

There is little consensus with regards to the most appropriate surgical management for low-grade appendiceal mucinous adenocarcinomas (LAMA), though right hemicolectomy is usually recommended. Source link

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Guideline on Diagnosis and Management of Precursors and Early Stages of Gastric Adenocarcinoma

New evidence-based recommendations for care of patients at risk for gastric adenocarcinoma Source link

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Molecular alterations and PD-L1 expression in non-ampullary duodenal adenocarcinoma: Associations among clinicopathological, immunophenotypic and molecular features

Molecular alterations and PD-L1 expression in non-ampullary duodenal adenocarcinoma: Associations among clinicopathological, immunophenotypic and molecular features Source link

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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma Source link

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Reproduction of molecular subtypes of gastric adenocarcinoma by transcriptome sequencing of archival tissue

Reproduction of molecular subtypes of gastric adenocarcinoma by transcriptome sequencing of archival tissue Source link

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Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma

Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma Source link

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Interactive decision support for esophageal adenocarcinoma screening and surveillance

A key barrier to controlling esophageal adenocarcinoma (EAC) is identifying those most likely to benefit from screening and surveillance. We aimed to develop an online educational tool, termed IC-RISC™, for...

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Perioperative chemotherapy feasible for resectable pancreatic adenocarcinoma

CHICAGO — Perioperative chemotherapy appeared feasible for patients with resectable pancreatic adenocarcinoma, according to randomized phase 2 study results presented at ASCO Annual Meeting.Safety results and resection rates also appeared...

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Early genome catastrophes can lead to development of lung cancer in non-smokers

Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers. Source link

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