adenocarcinoma
- December 5, 2019
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- Tags: adenocarcinomaColorectalCorrectiondeterminingGradeQualitativesignaturetranscriptional
Correction: A qualitative transcriptional signature for determining the grade of colorectal adenocarcinoma Source link
Read more- December 2, 2019
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- Tags: adenocarcinomaBRCA1BRCA2CharacteristicsductalGermlineMutationPALB2PancreaticpatientsPlatinumRESPONSE
Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation Source link
Read more- November 29, 2019
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- Tags: adenocarcinomaantipsychoticDiphenylbutylpiperidinedrugsductalGrowthinhibitmicePancreaticprolactinReceptorReducesignaling
Prolactin (PRL) signaling is upregulated in hormone-responsive cancers. The PRL receptor (PRLR) is class I cytokine receptor that signals via the JAK–STAT and MAPK pathways to regulate cell proliferation, migration,...
Read more- November 24, 2019
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- Tags: adenocarcinomaCirculatingDNAductalindicatormetaanalysisPancreaticprognosticResectableReviewSystematicTumor
Circulating tumor DNA as a prognostic indicator in resectable pancreatic ductal adenocarcinoma: A systematic review and meta-analysis Source link
Read more- November 21, 2019
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- Tags: adenocarcinomaBowelDetectiondiseaseDNADysplasiaGradeHighinflammatorypatientsStool
Stool DNA for the Detection of High Grade Dysplasia and Adenocarcinoma in Patients with Inflammatory Bowel Disease Source link
Read more- November 18, 2019
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- Tags: adenocarcinomaantagonismantiinvasiveDasatinibEffectsEnhancesMCL1Pancreatic
MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma Source link
Read more- November 15, 2019
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- Tags: adenocarcinomabasedDatagcForestGeneticLungMLWgcForestmodelMultimodalmultiweightedStaging
Lung cancer is one of the most common types of cancer, among which lung adenocarcinoma accounts for the largest proportion. Currently, accurate staging is a prerequisite for effective diagnosis and...
Read more- September 18, 2019
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- Tags: adenocarcinomacolonmiR1013ppathwayprogressionpromotesrectalsignalingSNHGWntβCatenin
Small nucleolar RNA host gene 6 (SNHG6) regulates diverse biological processes in cancers. Potential function of SNHG6 in human colon and rectal adenocarcinoma (CRC) was evaluated. Source link
Read more- September 9, 2019
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- Tags: adenocarcinomacancerCellInhibitorKRASLungnonsmallpatientsphaseshowsstudyTolerated
A clinical trial testing the toxicity of a KRAS inhibitor demonstrated early promising antitumor activity and few adverse side effects in patients with advanced non-small cell lung cancer harboring KRAS...
Read more- September 6, 2019
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- Tags: adenocarcinomaASGEBarrett's EsophagusBarrett039scancerEndoscopyEsophagusGuidelinereleasedscreeningsurveillanceupdated
The American Society for Gastrointestinal Endoscopy has released its updated "ASGE guideline on screening and surveillance of Barrett's esophagus," published in the September issue of GIE: Gastrointestinal Endoscopy. Source link
Read more- September 2, 2019
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- Tags: adenocarcinomaARHGEF10ductalexchangefactorGuaninenucleotidePancreaticputativeRhoSuppressorTumor
Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma Source link
Read more- August 30, 2019
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- Tags: adenocarcinomaAidcancerCellsGastroenterologyLaboratorymedicineMetastasisNerveOncologypainPancreaticPancreatic CancerpHresearchRevealsSpreadstudyTumor
A couple of molecules that nerve cells use to grow during development could help explain why the most common pancreatic cancers are so difficult to contain and for patients to...
Read more- August 28, 2019
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- Tags: adenocarcinomacancerDetectionEarlyimproveLineMetabolicopportunitiesPancreatictime
A reliable biomarker to detect pancreatic ductal adenocarcinoma (PDAC) continues to be elusive. With employing metabolomics we hypothesize that a broader analysis of systemic blood can differentiate different stages of...
Read more- August 23, 2019
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- Tags: adenocarcinomacancerCellChainCriticaldecodedrugsGrowthmoleculesOncogenePancreaticPancreatic CancerresearchResearcherssurvival
Researchers at Georgetown Lombardi Comprehensive Cancer Center have decoded a chain of molecules that are critical for the growth and survival of pancreatic ductal adenocarcinoma (PDAC)-;the most common and also...
Read more- August 21, 2019
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- Tags: adenocarcinomabreastBreast CancercancerCanineClinical TrialdiabetesDrugGeneGeneticGenomicGenomicshumanLungLung CancermedicineMutationNeratinibpublic healthresearchsmokingtobaccoTreatVeterinarywork
Despite those velvet paintings of poker-playing dogs smoking pipes, cigars and cigarettes, our canine friends really don't use tobacco. But like many humans who have never smoked, dogs still get...
Read more- August 18, 2019
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- Tags: adenocarcinomaAuthorCorrectionductalHeterogeneityHighlightsintratumoralMalignantPancreaticprogressionRNASeqsinglecell
Author Correction: Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma Source link
Read more- August 13, 2019
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- Tags: adenocarcinomacancerCellColorectalGenomicInsightsRareringSignetSubpopulation
Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma Source link
Read more- August 3, 2019
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- Tags: adenocarcinomaDuctGrowthPancreaticpromotessignalingTGFβtubestructureforming
TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma Source link
Read more- August 2, 2019
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- Tags: adenocarcinomacancerCelldiscoverydistinctdrugsFutureLungLung CancerPathwayspatientspHresearch
Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Source link
Read more- July 29, 2019
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- Tags: adenocarcinomaAppendicealHemicolectomylowgradeMucinouspatientsRole
There is little consensus with regards to the most appropriate surgical management for low-grade appendiceal mucinous adenocarcinomas (LAMA), though right hemicolectomy is usually recommended. Source link
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