Tag: activity

Biology

NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression [Research Article]

Newsemia
Proteasomes are protease complexes essential for cellular homeostasis, and their activity is crucial for cancer cell growth. However, the mechanism of how proteasome activity is...
Gastroenterology

JNJ-56136379, an HBV Capsid Assembly Modulator, is Well-Tolerated and Has Antiviral Activity in a Phase 1 Study of Patients with Chronic Infection

Newsemia
JNJ-56136379 (JNJ-6379), a capsid assembly modulator that blocks hepatitis B virus (HBV) replication, was well tolerated and demonstrated dose-proportional pharmacokinetics in healthy participants in part...
Pharma / Biotech

Swertiamarin, a secoiridoid glycoside modulates nAChR and AChE activity.

Newsemia
Related Articles Swertiamarin, a secoiridoid glycoside modulates nAChR and AChE activity. Exp Gerontol. 2020 Jun 23;:111010 Authors: Pandey T, Smita SS, Mishra A, Sammi SR,...
Biology

Reduced lactate dehydrogenase activity in the heart and suppressed sex hormone levels are associated with female-biased mortality during thermal stress in Pacific salmon [RESEARCH ARTICLE]

Newsemia
A. G. Little, E. Hardison, K. Kraskura, T. Dressler, T. S. Prystay, B. Hendriks, J. N. Pruitt, A. P. Farrell, S. J. Cooke, D. A....
Gastroenterology

Lysophosphatidic Acid Increases Maturation of Brush Borders and SGLT1 activity in MYO5B-deficient Mice, a Model of Microvillus Inclusion Disease

Newsemia
Myosin VB (MYO5B) is an essential trafficking protein for membrane recycling in gastrointestinal epithelial cells. The inactivating mutations of MYO5B cause the congenital diarrheal disease,...
Latest News

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

Newsemia
People suffering from rheumatoid arthritis with increased disease activity are more often affected by thrombosis. Source link...

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