Tag : activator

Pharma / Biotech

Development of a potent and orally active activator of adenosine monophosphate-activated protein kinase (AMPK), ASP4132, as a clinical candidate for the treatment of human cancer.

Newsemia
Related Articles Development of a potent and orally active activator of adenosine monophosphate-activated protein kinase (AMPK), ASP4132, as a clinical candidate for the treatment of...
Cardiology

In peripartum cardiomyopathy Plasminogen Activator Inhibitor-1 is a potential new biomarker with controversial roles.

Newsemia
Related Articles In peripartum cardiomyopathy Plasminogen Activator Inhibitor-1 is a potential new biomarker with controversial roles. Cardiovasc Res. 2019 Nov 11;: Authors: Ricke-Hoch M, Hoes...
Biology

Transcriptional Repression of the APC/C Activator Genes CCS52A1/A2 by the Mediator Complex Subunit MED16 Controls Endoreduplication and Cell Growth in Arabidopsis

Newsemia
Endoreduplication, the replication of the nuclear genome in the absence of mitosis, is often associated with cell growth and differentiation in plants and animals, but...
Cardiology

Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis.

Newsemia
Related Articles Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis. Catheter Cardiovasc Interv....
Latest News

Scientists identify endogenous activator of sigma-1 receptors in human cells

Newsemia
Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for...
Neurology

Ten-Year Evaluation of the TOYOTA Prehospital Stroke Scale for Tissue Plasminogen Activator Intravenous Therapy in the Real World.

Newsemia
Related Articles Ten-Year Evaluation of the TOYOTA Prehospital Stroke Scale for Tissue Plasminogen Activator Intravenous Therapy in the Real World. Cerebrovasc Dis. 2018 Nov 01;46(3-4):184-192...
Latest News

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3)

Newsemia
Shih, PC; Yang, Y; Parkinson, GN; Wilderspin, A; Wells, G; (2018) A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal...
Latest News

Plasminogen activator inhibitor-1 and tissue plasminogen activator and incident AF: Data from the PREVEND study

Newsemia
Mulder, BA; Geelhoed, B; van der Harst, P; Spronk, HM; Van Gelder, IC; Asselbergs, FW; Rienstra, M; (2018) Plasminogen activator inhibitor-1 and tissue plasminogen activator...
Neurology

Intravenous thrombolysis in stroke patients taking novel oral anticoagulants: experience with the low-dose 0.6 mg/kg of recombinant tissue-type plasminogen activator. Case reports

Newsemia
In the last decade, the novel oral anticoagulant (NOAC) dabigatran (a direct thrombin inhibitor), rivaroxaban, apixaban and edoxaban (direct factor Xa inhibitors) have been approved...

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