Tag : activator

Cardiology

The Cardiac Myosin Activator Omecamtiv Mecarbil Improves Left Ventricular Myocardial Deformation in Chronic Heart Failure (COSMIC-HF).

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Related Articles The Cardiac Myosin Activator Omecamtiv Mecarbil Improves Left Ventricular Myocardial Deformation in Chronic Heart Failure (COSMIC-HF). Circ Heart Fail. 2020 Nov 12;: Authors:...
Cardiology

Safety of low-dose prolonged infusion of tissue plasminogen activator therapy in patients with thromboembolic events in the intensive care unit.

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Related Articles Safety of low-dose prolonged infusion of tissue plasminogen activator therapy in patients with thromboembolic events in the intensive care unit. Kardiologiia. 2020 Aug...
Neurology

Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia.

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Related Articles Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia. J Neurosci. 2020 04 08;40(15):3119-3129 Authors: Flippo KH, Lin Z, Dickey AS, Zhou...
Pharma / Biotech

Development of a potent and orally active activator of adenosine monophosphate-activated protein kinase (AMPK), ASP4132, as a clinical candidate for the treatment of human cancer.

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Related Articles Development of a potent and orally active activator of adenosine monophosphate-activated protein kinase (AMPK), ASP4132, as a clinical candidate for the treatment of...
Cardiology

In peripartum cardiomyopathy Plasminogen Activator Inhibitor-1 is a potential new biomarker with controversial roles.

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Related Articles In peripartum cardiomyopathy Plasminogen Activator Inhibitor-1 is a potential new biomarker with controversial roles. Cardiovasc Res. 2019 Nov 11;: Authors: Ricke-Hoch M, Hoes...
Biology

Transcriptional Repression of the APC/C Activator Genes CCS52A1/A2 by the Mediator Complex Subunit MED16 Controls Endoreduplication and Cell Growth in Arabidopsis

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Endoreduplication, the replication of the nuclear genome in the absence of mitosis, is often associated with cell growth and differentiation in plants and animals, but...
Cardiology

Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis.

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Related Articles Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis. Catheter Cardiovasc Interv....
Latest News

Scientists identify endogenous activator of sigma-1 receptors in human cells

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Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for...
Neurology

Ten-Year Evaluation of the TOYOTA Prehospital Stroke Scale for Tissue Plasminogen Activator Intravenous Therapy in the Real World.

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Related Articles Ten-Year Evaluation of the TOYOTA Prehospital Stroke Scale for Tissue Plasminogen Activator Intravenous Therapy in the Real World. Cerebrovasc Dis. 2018 Nov 01;46(3-4):184-192...
Latest News

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3)

Newsemia
Shih, PC; Yang, Y; Parkinson, GN; Wilderspin, A; Wells, G; (2018) A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal...

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