Tag : activation

Biology

Dilp-2–mediated PI3-kinase activation coordinates reactivation of quiescent neuroblasts with growth of their glial stem cell niche

Newsemia
by Xin Yuan, Conor W. Sipe, Miyuki Suzawa, Michelle L. Bland, Sarah E. Siegrist Dietary nutrients provide macromolecules necessary for organism growth and development. In...
Gastroenterology

Activation of estrogen receptor can impede growth of pancreatic cancer cells

Newsemia
Activating the G protein-coupled estrogen receptor – a receptor found on the surface of many normal and cancer tissues – has been shown to stop...
Biology

Visualization of two architectures in class-II CAP-dependent transcription activation

Newsemia
by Wei Shi, Yanan Jiang, Yibin Deng, Zigang Dong, Bin Liu Transcription activation by cyclic AMP (cAMP) receptor protein (CAP) is the classic paradigm of...
Gastroenterology

SPOCK1 overexpression induced by platelet-derived growth factor-BB promotes hepatic stellate cell activation and liver fibrosis through the integrin α5β1/PI3K/Akt signaling pathway

Newsemia
SPOCK1 overexpression induced by platelet-derived growth factor-BB promotes hepatic stellate cell activation and liver fibrosis through the integrin α5β1/PI3K/Akt signaling pathway Source link...
Latest News

Pathogenic Activation of Mesenchymal Stem Cells is induced by the Disease Microenvironment in Systemic Sclerosis

Newsemia
Stratton, R; Taki, Z; Denton, C; Ahmed Abdi, B; (2020) Pathogenic Activation of Mesenchymal Stem Cells is induced by the Disease Microenvironment in Systemic Sclerosis....
Neurology

Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation

Newsemia
Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). Levodopa (L-Dopa), the current main treatment for...
Biology

A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers

Newsemia
by Kunming Zhao, Xingwen Wang, Xuting Xue, Li Li, Ying Hu Ataxia-telangiectasia mutated (ATM) is an apical kinase of the DNA damage response following DNA...
Pediatrics

Sex differences in blood pro-oxidant status and platelet activation in children admitted with respiratory syncytial virus bronchiolitis: a pilot study

Newsemia
Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in the pediatric population worldwide and an important cause of death in developing countries....
Cardiology

5F peptide promotes endothelial differentiation of bone marrow stem cells through activation of ERK1/2 signaling.

Newsemia
Related Articles 5F peptide promotes endothelial differentiation of bone marrow stem cells through activation of ERK1/2 signaling. Eur J Pharmacol. 2020 Mar 04;:173051 Authors: Zhang...
Cardiology

Dihydromyricetin alleviates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome through activation of SIRT1.

Newsemia
Related Articles Dihydromyricetin alleviates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome through activation of SIRT1. Biochem Pharmacol. 2020 Feb 26;:113888 Authors: Sun Z, Lu W, Lin...
Pharma / Biotech

β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression.

Newsemia
Related Articles β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression. Phytomedicine. 2020 Feb 07;69:153183...

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