Neurology

PDE10A antibodies in autoimmune encephalitis: A possible marker of cancer immunotherapy?

Although paraneoplastic neurologic syndromes have been known for over half a century, developments during the last decade have reshaped the field of autoimmune neurology. The discovery of over 15 new...

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What's happening in Neurology(R) Clinical Practice

Articles appearing in the October 2018 issue Source link

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What's happening in Neurology(R) Neuroimmunology & Neuroinflammation

Dear Authors, Source link

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Segmental spinal sympathetic machinery: Implications for autonomic dysreflexia

The sympathetic nervous system has a critical role in maintenance of arterial blood pressure; regulation of regional blood flow; thermoregulation; and integrated response to exercise, disturbances in homeostasis, and external...

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Clinician-rated measures for distal symmetrical axonal polyneuropathy: ACTTION systematic review

Distal symmetrical axonal polyneuropathy (DSP) is due to injury to peripheral sensory, motor, and autonomic nerve fibers, resulting in distal predominant sensory loss, pain, and gait instability. DSP occurs as...

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Monocular nystagmus in a patient with alternating hemiplegia of childhood

Monocular nystagmus is a rare condition that occurs in limited number of disorders, such as spasmus nutans, multiple sclerosis, and alternating hemiplegia of childhood (AHC).1 AHC is a neurodevelopmental disorder...

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INTREPAD: A randomized trial of naproxen to slow progress of presymptomatic Alzheimer disease

In the article "The genetic basis of undiagnosed muscular dystrophies and myopathies: Results from 504 patients" by Savarese et al.,1 the degree listed for the eleventh author, Dr. Alessandra Ruggieri, should...

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Hospital distance, socioeconomic status, and timely treatment of ischemic stroke

Objective To determine whether lower socioeconomic status (SES) and longer home to hospital driving time are associated with reductions in tissue plasminogen activator (tPA) administration and timeliness of the treatment....

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Mild behavioral impairment is linked to worse cognition and brain atrophy in Parkinson disease

Objective To evaluate the associations of mild behavioral impairment (MBI) with cognitive deficits and patterns of gray matter changes in Parkinson disease (PD). Methods Sixty patients with PD without dementia...

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Measures of obesity are associated with MRI markers of brain aging: The Northern Manhattan Study

Objective To examine associations between measures of obesity in middle to early-old age with later-life MRI markers of brain aging. Methods We analyzed data from the Northern Manhattan MRI Sub-Study...

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Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity

Objective To describe a novel antibody biomarker of neurologic paraneoplastic autoimmunity specific for phosphodiesterase 10A (PDE10A), a striatum-enriched phosphodiesterase, and to characterize the clinical phenotype of patients with PDE10A immunoglobulin...

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Teaching NeuroImages: Enlarged parietal foramina inadvertently labeled as burr holes

A 49-year-old woman presented with status migrainosus. A CT head revealed only bilateral symmetric burr holes in the posterior paramedian calvarium despite no prior cranial surgery (figure). These holes ultimately...

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Dalfampridine improves slowed processing speed in MS: Picking up the pace

Cognitive decline is recognized as a prevalent and debilitating symptom of multiple sclerosis (MS),1 with cognitive changes often occurring early in the disease course.2 Even relatively subtle cognitive decline can...

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Teaching NeuroImages: Optic and third cranial nerves infiltration as initial relapse of acute lymphoblastic leukemia

A 34-year-old man with a history of acute lymphoblastic leukemia (ALL) under consolidation treatment presented right-side blurred vision and headache associated with complete third right cranial nerve palsy. Brain MRI...

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Quantitative EEG reactivity and machine learning for prognostication in hypoxic-ischemic brain injury.

Related Articles Quantitative EEG reactivity and machine learning for prognostication in hypoxic-ischemic brain injury. Clin Neurophysiol. 2019 Jul 25;130(10):1908-1916 Authors: Amorim E, van der Stoel M, Nagaraj SB, Ghassemi MM,...

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npr: Scientists may have caught a glimpse of what sadness looks…

npr: Scientists may have caught a glimpse of what sadness looks like in the brain.A study of 21 people found that for most, feeling down was associated with greater communication...

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Can Being Overweight Contribute to My Depression?

Being overweight can make you feel bad about the way you look and feel like a failure if you can’t stick to a healthy diet. But can it actually contribute...

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Researcher decodes the brain to help patients with mental illnesses

Specific algorithms and brain signatures can be used to tell when a person is focused, indicating who may be able to benefit from electrical stimulation to help boost attention. The...

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Cerebral hemodynamic changes during motor imagery and passive robot-assisted movement of the lower limbs

Neurovascular Coupling is the cerebral mechanism responsible for linking neuronal activity, cerebral metabolism and regional cerebral blood flow (CBF). The direct relation between functional brain activity during active, passive and...

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Alzheimer’s disease risk gene is involved in synaptic transmission

A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility. Source link

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