Biology

Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity





Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity
Maria Zachari, Marianna Longo, Ian G Ganley

Pharmacological inhibition of ULK1 with multiple and distinct small molecules does not block autophagosome initiation but does impair autophagic flux.



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