Gastroenterology

Nivolumab plus chemotherapy prolongs PFS in gastric, gastroesophageal junction cancer



The addition of nivolumab to first-line chemotherapy significantly improved PFS, but not OS, for patients with advanced or recurrent HER2-negative gastric and gastroesophageal junction cancer, according to phase 3 study findings.
Results of the double-blind, randomized ATTRACTION-4 trial, presented at ESMO Virtual Congress 2020, also showed a higher objective response rate and more durable responses with the combination than with chemotherapy alone, researchers noted.
“Nivolumab [Opdivo, Bristol Myers Squibb] has shown significant survival benefit for heavily pretreated patients with

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