AI/ML

Trialstreamer: A living, automatically updated database of clinical trial reports.


Icon for Silverchair Information Systems Related Articles

Trialstreamer: A living, automatically updated database of clinical trial reports.

J Am Med Inform Assoc. 2020 Sep 17;:

Authors: Marshall IJ, Nye B, Kuiper J, Noel-Storr A, Marshall R, Maclean R, Soboczenski F, Nenkova A, Thomas J, Wallace BC

Abstract
OBJECTIVE: Randomized controlled trials (RCTs) are the gold standard method for evaluating whether a treatment works in health care but can be difficult to find and make use of. We describe the development and evaluation of a system to automatically find and categorize all new RCT reports.
MATERIALS AND METHODS: Trialstreamer continuously monitors PubMed and the World Health Organization International Clinical Trials Registry Platform, looking for new RCTs in humans using a validated classifier. We combine machine learning and rule-based methods to extract information from the RCT abstracts, including free-text descriptions of trial PICO (populations, interventions/comparators, and outcomes) elements and map these snippets to normalized MeSH (Medical Subject Headings) vocabulary terms. We additionally identify sample sizes, predict the risk of bias, and extract text conveying key findings. We store all extracted data in a database, which we make freely available for download, and via a search portal, which allows users to enter structured clinical queries. Results are ranked automatically to prioritize larger and higher-quality studies.
RESULTS: As of early June 2020, we have indexed 673 191 publications of RCTs, of which 22 363 were published in the first 5 months of 2020 (142 per day). We additionally include 304 111 trial registrations from the International Clinical Trials Registry Platform. The median trial sample size was 66.
CONCLUSIONS: We present an automated system for finding and categorizing RCTs. This yields a novel resource: a database of structured information automatically extracted for all published RCTs in humans. We make daily updates of this database available on our website (https://trialstreamer.robotreviewer.net).

PMID: 32940710 [PubMed – as supplied by publisher]

Source link

Related posts

Former Google Chief to Chair Government AI Advisory Group

Newsemia

The Holy Grail of Artificial Intelligence – Walter Bradley Center for Natural and Artificial Intelligence

Newsemia

Redash Dashboard Tutorial with Cube.js

Newsemia

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy

COVID-19

COVID-19 (Coronavirus) is a new illness that is having a major effect on all businesses globally LIVE COVID-19 STATISTICS FOR World