Gastroenterology

Nidufexor significantly reduces ALT levels, hepatic fat in NASH





Two dosages of nidufexor were safe and correlated with significant reductions in alanine aminotransferase levels, hepatic fat fraction and body weight in patients with nonalcoholic steatohepatitis, according to research presented at The Digital International Liver Congress.
“Nidufexor proved safe and generally well tolerated,” Richard Aspinall, BSc, MBChB, PhD, MRCP, from the department of gastroenterology and hepatology at Queen Alexandra Hospital Portsmouth, United Kingdom, said during his presentation. “The most common adverse event was pruritus, particularly in the higher

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