Biology

PhD student position in the Pinto-Teixeira lab at the CBI, Toulouse, France


The successful candidate will join the Neural Circuit Development Lab at the Center for Integrative Biology (CBI) in Toulouse, on a project aimed at studying neural circuit assembly in Drosophila. The position should ideally be filled by October 2020.

Background and aim of the project

We use the fruit fly Drosophila melanogaster visual system as a model to study the genetic, molecular and cellular mechanisms that regulate wiring specificity, from development to circuit function.

In the fly, as in humans, dedicated sets of neurons process directional visual motion information: some neurons are sensitive to a stimulus presented to the eye moving from left to right, others top to bottom, and so forth. Each neuron type is characterized by a combination of specific morphological attributes that dictate the neuron’s direction selectivity.

We have previously identified the mechanisms by which neuroprogenitors generate all motion sensing neurons in the fly (Pinto-Teixeira, Cell 2018). Departing from these findings, this project combines molecular genetic tools, live imaging approaches, Drosophila transgenesis, immuno histochemistry and transcriptomics to identify the developmental programs that differentiate and wire each motion sensing neuron to establish its directional motion preference.

Profile

We are seeking an enthusiastic, creative and friendly individual to join our growing team. The candidate should hold a Master’s degree (M. Sc), have a strong interest in neuronal differentiation, neural circuit formation and developmental neurobiology. Previous experience working with Drosophila is preferable, but not essential. Proficiency in English is absolutely required.

The lab

The Neural Circuit Development Lab is a young and international lab, funded by the Fondation Bettencourt Schueller, ATIP-AVENIR, CNRS, University Paul Sabatier and the CBI.

The CBI is a multidisciplinary institute comprising 40 research teams, including a community of 9 fly labs. The Neural Circuit Development Lab is at the crossroads between the Stem Cells and Development Biology, and the Molecular and Cellular Neurobiology Programs.

Toulouse is the fourth-largest city in France, housing three top-ranked universities with the second largest student population in the country. Students consistently rank Toulouse among the best French cities to live and study.

Application

Interested applicants please address applications as a single PDF file, including:

  • a personal statement
  • CV
  • and the contact of two referees

to Dr. Filipe Pinto Teixeira at filipe.pinto-teixeira@univ-tlse3.fr.

 

Review of applications will begin immediately and continue until position is filled.

 

For more information please visit www.pintoteixeiralab.com

 

 

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