TNF inhibitors linked to greater risk for inflammatory central nervous system events

The use of TNF inhibitors among patients with autoimmune disease may be associated with an increased risk for inflammatory central nervous system events, according to data published in JAMA Neurology.
“After the introduction of TNF inhibitors, several studies reported an association between TNF inhibitors and inflammatory demyelinating central nervous system (CNS) events such as optic neuritis, transverse myelitis and multiple sclerosis (MS), and neuromyelitis optica spectrum disorder (NMOSD),” Amy Kunchok, MBBS, MMed, of the Mayo Clinic, in Rochester, Minn., and colleagues wrote.

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