Neurology

Author response: RCVS2 score and diagnostic approach for reversible cerebral vasoconstriction syndrome


We thank Drs. Yuan and Hu for their comments. We already acknowledged the sample size limitation, the need for external validation, the need to assess RCVS2 score performance in distinguishing RCVS from arteriopathies other than primary angiitis of the CNS, and that advanced vessel wall imaging or biomarker studies are unlikely to improve on the near-perfect performance of RCVS2 scores >5 or <2 (but may have some utility in patients with intermediate scores 3 or 4).1 With regard to a possible high false-positive rate for thunderclap headache and vasoconstrictive triggers, we believe that this is unlikely. Thunderclap headache is a unique and unforgettable symptom, so documentation is usually accurate. Patients tend to underreport vasoconstrictive triggers such as illicit drugs and over-the-counter medications, so a high false-negative rate is more likely.

Source link

Related posts

Dr. Steven DeKosky — The importance of early Alzheimer’s diagnosis

Newsemia

Low Back Pain Common in the Progression of Parkinson Disease

Newsemia

Amusement Parks and Kids with ADHD – Managing Expectations

Newsemia

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy

COVID-19

COVID-19 (Coronavirus) is a new illness that is having a major effect on all businesses globally LIVE COVID-19 STATISTICS FOR World