Latest News

Potential upgrades on in vitro toxicological cell-based models




Over the last 100 years, knowledge regarding drug toxicity has increased significantly, especially since the thalidomide tragedy of the mid-20th century. This tragedy marked the beginning of rigorous drug approval and monitoring systems, and marketed drugs are much safer nowadays. However, there are still many uncertainties regarding the testing of novel drugs, especially considering the existing models, which do not always cover all important aspects of the physiology. Unfortunately, omission of some of these aspects still causes tragedies following the actual drug validation process, for example, in the U.K. in 2006 (TGN1412), and in France in 2016 (BIA 10-2474).

Source link




Related posts

U.S. Suicide Rate Rose 33% Between 1999 and 2017

Newsemia

Systematic taxonomy of the Trilobatus sacculifer plexus and descendant Globigerinoidesella fistulosa (planktonic foraminifera)

Newsemia

Micropep Technologies Strengthens Its Management Team by Appointing Dr. Mikael Courbot as Chief Technical Officer

Newsemia

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy