Gastroenterology

No evidence for link between PPIs and dementia




Researchers found no clinically meaningful association between short-term proton pump inhibitor therapy and increased risk for dementia, according to the results of a meta-analysis.
Colin W. Howden, MD, FACG, Hyman Professor of Medicine and chief of the division of gastroenterology at the University of Tennessee Health Science Center, and colleagues wrote that proton pump inhibitors have been linked with adverse events in the past, including dementia. However, studies that have explored these risks have returned conflicting results.
“Proton pump inhibitors are widely used but, in recent

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