Alternative dosing regimens for atezolizumab: right dose, wrong frequency.
Cancer Chemother Pharmacol. 2019 Oct 19;:
Authors: Goldstein DA, Ratain MJ
The population pharmacokinetics of atezolizumab demonstrate that the trough concentrations are well above the putative target of 6 µg/ml. Thus, alternative dosing schedules are indeed of interest, focusing on reducing the frequency to allow greater patient convenience and reduced costs.
PMID: 31630223 [PubMed – as supplied by publisher]