Scientists create brain-mimicking environment to grow 3D tissue models of brain tumors

Researchers have developed 3-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix (ECM) — the complex network of proteins and amino acids with bound sugars that not only provides support for surrounding neural tissue, but also helps to guide cell growth and development. The development represents a significant advancement for the study of brain tumor biology and pharmacological response.

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