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Giving trauma patients blood pressure stabilizing hormone cuts transfusions by half

Giving trauma patients with severe blood loss the hormone arginine vasopressin (AVP) cut the volume of blood products required to stabilize them by half, according to results of a new, first-of-its-kind clinical trial from Penn Medicine. The finding, published online this week in JAMA Surgery, suggests that administering AVP to trauma patients with severe bleeding could become standard practice in trauma care, reducing the use of blood products and their adverse side effects. The authors say the study is particularly important for the treatment of patients with gun-related injuries. Each year, there are over 100,00 firearm-related injuries with over 36,000 deaths.

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