Gastroenterology

CRC rates low after negative FIT regardless of cutoff

Incidence of interval colorectal cancer after a negative result from a fecal immunochemical test is low, according to data collected from a population-based screening program.
Esther Toes-Zoutendijk, of the department of public health at Erasmus MC University Medical Center in the Netherlands, and colleagues wrote that although FIT has shown to be effective in detecting CRC at low cutoffs or at short screening intervals, programs often use higher cutoffs to find a balance between true and false positives.
To explore the effects of different cutoff values, researchers analyzed data collected

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