The effect of xenon-augmented sevoflurane-anaesthesia on intra-operative haemodynamics and postoperative neurocognitive function in children undergoing cardiac catheterization: a one-year follow up of a randomized controlled pilot trial.

Paediatr Anaesth. 2019 Jul 09;:

Authors: Devroe S, Lemiere J, Rex S

Abstract
We recently reported that in children between 4 and 12 years of age, suffering from congenital heart disease and undergoing cardiac catheterization, combining xenon with sevoflurane was safe and feasible.(1) In this population, after induction of anaesthesia with propofol-fentanyl-rocuronium, standardized anaesthesia maintained with sevoflurane titrated to a BIS-value of 40-60 (mean 2.04 vol-% [IQR 1.80-2.22]) resulted in short-lasting neurocognitive deficits when compared to a non-randomized group of healthy control children matched for age and gender. This article is protected by copyright. All rights reserved.

PMID: 31287192 [PubMed – as supplied by publisher]

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