Gastroenterology

Remission of Bile Acid Malabsorption Symptoms Following Treatment With the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

As many as 50% of patients with chronic diarrhea may suffer from bile acid malabsorption (BAM).1 BAM is associated with spillover of bile acids from the small intestine to the colon, triggering osmotic-induced fluid secretion with subsequent watery diarrhea and high stool frequency alongside gastrointestinal symptoms, such as abdominal pain and bloating.1 The gold standard for the diagnosis of BAM is the 75selenium-homotaurocholic acid test (SeHCAT), which evaluates the 7-day retention of orally administered 75selenium-labeled bile acids.

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