3-V Biosciences dosed its first patient in a phase 2 clinical trial of a fatty acid inhibitor candidate from Ascletis for the treatment of nonalcoholic steatohepatitis, according to a press release.
“Lipid synthesis is an important driver of NASH,” Rohit Loomba, MD, from the University of California San Diego, and coordinating investigator of the phase 2 study, said in the release. “The imaging techniques in this study will give us a very clear understanding of the impact this drug has on liver fat, a key driver of this disease.”
TVB-2640 is an orally bioavailable

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