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Mortality-specific comorbidity among inpatients with ischemic stroke in West China.

Acta Neurol Scand. 2019 Apr 29;:

Authors: Si Y, Xiao X, Xiang S, Guo J, Yu N, Mo Q, Guo F, Sun H

OBJECT: This study aimed to investigate the current condition of mortality-specific comorbidity among hospitalized patients with ischemic stroke.
METHODS: Five-year data of inpatients with ischemic stroke (IS) were extracted from the hospital medical database. A retrospective review of eighteen mortality-specific comorbidities in extensively validated Charlson Comorbidity Index (CCI) was carried out for each patient. In addition, the distribution of the CCI -based prognostic score was calculated.
RESULTS: A total of 10331 (male 57.6%) cases with IS were recruited in the present study. The most prevalent mortality-specific comorbidities from high to low were: peripheral vascular disease (35.1%), diabetes uncomplicated (25.2%),mild liver disease (18.3%), chronic pulmonary disease (14.7%), congestive heart failure (10.8%), atrial fibrillation or flutter (10.3%), diabetes complicated (9.1%), moderate or severe renal disease (7.5%), dementia (7.1%). High prevalence of comorbidities in the elderly was also noted (31.1% patients with score≥3). Spearman correlation analysis with a rho of 0.25 (p < 0.001) showed a mild correlation between the age and the CCI- based prognostic score.
CONCLUSION: High prevalence of peripheral vascular disease, diabetes, liver disease, chronic pulmonary disease, congestive heart failure, atrial fibrillation or flutter, as major contributors to mortality were presented in in-hospital patients with IS in our area. One third of old patients with IS expose high mortality risk with the CCI score≥3. Early prevention and management of the potential comorbidities are necessary to reduce the mortality. This article is protected by copyright. All rights reserved.

PMID: 31032888 [PubMed – as supplied by publisher]

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