Two large ‘real-world’ studies conducted in Germany and the USA have confirmed the high rates of sustained virological response (SVR) observed in controlled clinical studies of glecaprevir/pibrentasvir (G/P) involving individuals with hepatitis C virus (HCV) infection. Across the two studies, which were presented today at The International Liver Congress 2019 in Vienna, Austria, a range of treatment-naïve and treatment-experienced individuals received G/P therapy, including those who are usually underrepresented in clinical trials such as patients receiving opioid substitution therapy, those with alcohol and/or active drug abuse, and those with psychiatric conditions and/or HIV coinfection.

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