Using 3 prospective observational cohorts including 1,288 patients with available clinical and pathologic data, Arvanitakis et al. estimated the association between longitudinal blood pressure (BP) measures and the risk of histopathologic cerebral infarctions. The investigators observed that, for a patient whose mean systolic BP (SBP) was 1 SD above the cohort’s mean SBP, that patient would be at a 46% increased risk of any cerebral infarction.

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